An Inhibitory Carboxyl-Terminal Domain in Ets-1 and Ets-2 Mediates Differential Binding of ETS Family Factors to Promoter Sequences of the mb-1 Gene

The mb-1 gene is expressed only during the early stages of B-lymphocyte differentiation. Here we show that the mb-1 proximal promoter region contains a functionally important binding site for members of the ETS family of DNA-binding proteins. We found that both the E26 virus-encoded v-ets and the my...

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