TLR4 Endogenous Ligand S100A8/A9 Levels in Adult-Onset Still's Disease and Their Association with Disease Activity and Clinical Manifestations

S100A8/A9 has been suggested as a marker of disease activity in patients with adult-onset Still's disease (AOSD). We evaluated the clinical significance of S100A8/A9 as a biomarker and its pathogenic role in AOSD. Blood samples were collected prospectively from 20 AOSD patients and 20 healthy c...

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Veröffentlicht in:	International journal of molecular sciences 2016-08, Vol.17 (8), p.1342-1342
Hauptverfasser:	Kim, Hyoun-Ah, Han, Jae Ho, Kim, Woo-Jung, Noh, Hyun Jin, An, Jeong-Mi, Yim, Hyunee, Jung, Ju-Yang, Kim, You-Sun, Suh, Chang-Hee
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arthritis, Rheumatoid - blood Arthritis, Rheumatoid - metabolism Arthritis, Rheumatoid - pathology Biomarkers C-Reactive Protein - metabolism Calgranulin A - blood Calgranulin A - metabolism Calgranulin B - blood Calgranulin B - metabolism Female Humans Interleukin-1beta - blood Kinases Leukocytes, Mononuclear - metabolism Ligands Male Middle Aged Pathogens Prospective Studies Signal Transduction - physiology Still's Disease, Adult-Onset - blood Still's Disease, Adult-Onset - immunology Still's Disease, Adult-Onset - metabolism Still's Disease, Adult-Onset - pathology Toll-Like Receptor 4 - metabolism Tumor Necrosis Factor-alpha - blood
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