Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin
While the cytological features of hepatocellular carcinoma on fine needle aspiration cytology are well described, cases of hepatocellular carcinoma with malignant cells in ascitic fluid and their characteristics are not. A patient is described with cirrhosis resulting from chronic hepatitis B virus...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical pathology 1997-05, Vol.50 (5), p.442-444 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 444 |
|---|---|
| container_issue | 5 |
| container_start_page | 442 |
| container_title | Journal of clinical pathology |
| container_volume | 50 |
| creator | Stephen, M R Oien, K Ferrier, R K Burnett, R A |
| description | While the cytological features of hepatocellular carcinoma on fine needle aspiration cytology are well described, cases of hepatocellular carcinoma with malignant cells in ascitic fluid and their characteristics are not. A patient is described with cirrhosis resulting from chronic hepatitis B virus infection, ascites, and hepatocellular carcinoma diagnosed by effusion cytology. The malignant cells in the effusion were shown to be positive for alpha fetoprotein using immunocytochemistry, and for human albumin using in situ hybridisation, confirming the diagnosis of hepatocellular carcinoma. Further investigations in a terminally ill patient were thus avoided. |
| doi_str_mv | 10.1136/jcp.50.5.442 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_499952</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3971438311</sourcerecordid><originalsourceid>FETCH-LOGICAL-b505t-1956e2e723eb9728f18e24903e8ba3c44319ae52e6fb7f55fbbf0e8dcd5742733</originalsourceid><addsrcrecordid>eNp9kc1vEzEQxS0EKmnhxhXJEggubPDnen3ggKLSIhUQUuHQi2U7duOwa6f2biH_PY4SRcCB0xze743ezAPgGUZzjGn7dm03c47mfM4YeQBmmAnSMMzah2CGEMGNFKx9DE5LWSOEqcD0BJxIgjmmdAZuzr2fSkgR2u2Y-nS7hcnDldvoMVnX91OvM7Q62xDToOHPMK5giLCEcYKrrclhGYoed36fMlxNg45Q92YaQnwCHnndF_f0MM_Atw_n14vL5urLxcfF-6vGcMTHBkveOuIEoc5IQTqPO0eYRNR1RlPLGMVSO05c643wnHtjPHLd0i65YERQegbe7fduJjO4pXVxzLpXmxwGnbcq6aD-VmJYqdt0r5iUkpPqf3Xw53Q3uTKqIZTd7Tq6NBUlZH0z5ryCL_4B12nKsd6msBCI8Y5hWak3e8rmVEp2_pgEI7UrTNXCFEeKq1pYxZ__mf4IHxqq-suDrovVvc862lCOGGllfSCuWLPHQhndr6Os8w_VCiq4-vx9oa4vv17cUNypT5V_vefNsP5_wN_uN7ua</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770458419</pqid></control><display><type>article</type><title>Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Stephen, M R ; Oien, K ; Ferrier, R K ; Burnett, R A</creator><creatorcontrib>Stephen, M R ; Oien, K ; Ferrier, R K ; Burnett, R A</creatorcontrib><description>While the cytological features of hepatocellular carcinoma on fine needle aspiration cytology are well described, cases of hepatocellular carcinoma with malignant cells in ascitic fluid and their characteristics are not. A patient is described with cirrhosis resulting from chronic hepatitis B virus infection, ascites, and hepatocellular carcinoma diagnosed by effusion cytology. The malignant cells in the effusion were shown to be positive for alpha fetoprotein using immunocytochemistry, and for human albumin using in situ hybridisation, confirming the diagnosis of hepatocellular carcinoma. Further investigations in a terminally ill patient were thus avoided.</description><identifier>ISSN: 0021-9746</identifier><identifier>EISSN: 1472-4146</identifier><identifier>DOI: 10.1136/jcp.50.5.442</identifier><identifier>PMID: 9215133</identifier><identifier>CODEN: JCPAAK</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and Association of Clinical Pathologists</publisher><subject>Albumins - metabolism ; Ascitic Fluid - chemistry ; Biological and medical sciences ; Biomarkers, Tumor - metabolism ; Biopsy, Needle ; Carcinoma, Hepatocellular - diagnosis ; Carcinoma, Hepatocellular - metabolism ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; In Situ Hybridization ; Liver Neoplasms - diagnosis ; Liver Neoplasms - metabolism ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Medical sciences ; Middle Aged ; Tumors</subject><ispartof>Journal of clinical pathology, 1997-05, Vol.50 (5), p.442-444</ispartof><rights>1997 INIST-CNRS</rights><rights>Copyright BMJ Publishing Group LTD May 1997</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b505t-1956e2e723eb9728f18e24903e8ba3c44319ae52e6fb7f55fbbf0e8dcd5742733</citedby><cites>FETCH-LOGICAL-b505t-1956e2e723eb9728f18e24903e8ba3c44319ae52e6fb7f55fbbf0e8dcd5742733</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC499952/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC499952/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2691951$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9215133$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stephen, M R</creatorcontrib><creatorcontrib>Oien, K</creatorcontrib><creatorcontrib>Ferrier, R K</creatorcontrib><creatorcontrib>Burnett, R A</creatorcontrib><title>Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin</title><title>Journal of clinical pathology</title><addtitle>J Clin Pathol</addtitle><description>While the cytological features of hepatocellular carcinoma on fine needle aspiration cytology are well described, cases of hepatocellular carcinoma with malignant cells in ascitic fluid and their characteristics are not. A patient is described with cirrhosis resulting from chronic hepatitis B virus infection, ascites, and hepatocellular carcinoma diagnosed by effusion cytology. The malignant cells in the effusion were shown to be positive for alpha fetoprotein using immunocytochemistry, and for human albumin using in situ hybridisation, confirming the diagnosis of hepatocellular carcinoma. Further investigations in a terminally ill patient were thus avoided.</description><subject>Albumins - metabolism</subject><subject>Ascitic Fluid - chemistry</subject><subject>Biological and medical sciences</subject><subject>Biomarkers, Tumor - metabolism</subject><subject>Biopsy, Needle</subject><subject>Carcinoma, Hepatocellular - diagnosis</subject><subject>Carcinoma, Hepatocellular - metabolism</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>In Situ Hybridization</subject><subject>Liver Neoplasms - diagnosis</subject><subject>Liver Neoplasms - metabolism</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Tumors</subject><issn>0021-9746</issn><issn>1472-4146</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1997</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kc1vEzEQxS0EKmnhxhXJEggubPDnen3ggKLSIhUQUuHQi2U7duOwa6f2biH_PY4SRcCB0xze743ezAPgGUZzjGn7dm03c47mfM4YeQBmmAnSMMzah2CGEMGNFKx9DE5LWSOEqcD0BJxIgjmmdAZuzr2fSkgR2u2Y-nS7hcnDldvoMVnX91OvM7Q62xDToOHPMK5giLCEcYKrrclhGYoed36fMlxNg45Q92YaQnwCHnndF_f0MM_Atw_n14vL5urLxcfF-6vGcMTHBkveOuIEoc5IQTqPO0eYRNR1RlPLGMVSO05c643wnHtjPHLd0i65YERQegbe7fduJjO4pXVxzLpXmxwGnbcq6aD-VmJYqdt0r5iUkpPqf3Xw53Q3uTKqIZTd7Tq6NBUlZH0z5ryCL_4B12nKsd6msBCI8Y5hWak3e8rmVEp2_pgEI7UrTNXCFEeKq1pYxZ__mf4IHxqq-suDrovVvc862lCOGGllfSCuWLPHQhndr6Os8w_VCiq4-vx9oa4vv17cUNypT5V_vefNsP5_wN_uN7ua</recordid><startdate>19970501</startdate><enddate>19970501</enddate><creator>Stephen, M R</creator><creator>Oien, K</creator><creator>Ferrier, R K</creator><creator>Burnett, R A</creator><general>BMJ Publishing Group Ltd and Association of Clinical Pathologists</general><general>BMJ</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19970501</creationdate><title>Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin</title><author>Stephen, M R ; Oien, K ; Ferrier, R K ; Burnett, R A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b505t-1956e2e723eb9728f18e24903e8ba3c44319ae52e6fb7f55fbbf0e8dcd5742733</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1997</creationdate><topic>Albumins - metabolism</topic><topic>Ascitic Fluid - chemistry</topic><topic>Biological and medical sciences</topic><topic>Biomarkers, Tumor - metabolism</topic><topic>Biopsy, Needle</topic><topic>Carcinoma, Hepatocellular - diagnosis</topic><topic>Carcinoma, Hepatocellular - metabolism</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>In Situ Hybridization</topic><topic>Liver Neoplasms - diagnosis</topic><topic>Liver Neoplasms - metabolism</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stephen, M R</creatorcontrib><creatorcontrib>Oien, K</creatorcontrib><creatorcontrib>Ferrier, R K</creatorcontrib><creatorcontrib>Burnett, R A</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stephen, M R</au><au>Oien, K</au><au>Ferrier, R K</au><au>Burnett, R A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin</atitle><jtitle>Journal of clinical pathology</jtitle><addtitle>J Clin Pathol</addtitle><date>1997-05-01</date><risdate>1997</risdate><volume>50</volume><issue>5</issue><spage>442</spage><epage>444</epage><pages>442-444</pages><issn>0021-9746</issn><eissn>1472-4146</eissn><coden>JCPAAK</coden><abstract>While the cytological features of hepatocellular carcinoma on fine needle aspiration cytology are well described, cases of hepatocellular carcinoma with malignant cells in ascitic fluid and their characteristics are not. A patient is described with cirrhosis resulting from chronic hepatitis B virus infection, ascites, and hepatocellular carcinoma diagnosed by effusion cytology. The malignant cells in the effusion were shown to be positive for alpha fetoprotein using immunocytochemistry, and for human albumin using in situ hybridisation, confirming the diagnosis of hepatocellular carcinoma. Further investigations in a terminally ill patient were thus avoided.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and Association of Clinical Pathologists</pub><pmid>9215133</pmid><doi>10.1136/jcp.50.5.442</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-9746 |
| ispartof | Journal of clinical pathology, 1997-05, Vol.50 (5), p.442-444 |
| issn | 0021-9746 1472-4146 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_499952 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Albumins - metabolism Ascitic Fluid - chemistry Biological and medical sciences Biomarkers, Tumor - metabolism Biopsy, Needle Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - metabolism Female Gastroenterology. Liver. Pancreas. Abdomen Humans In Situ Hybridization Liver Neoplasms - diagnosis Liver Neoplasms - metabolism Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Middle Aged Tumors |
| title | Effusion cytology of hepatocellular carcinoma with in situ hybridisation for human albumin |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-03T10%3A50%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effusion%20cytology%20of%20hepatocellular%20carcinoma%20with%20in%20situ%20hybridisation%20for%20human%20albumin&rft.jtitle=Journal%20of%20clinical%20pathology&rft.au=Stephen,%20M%20R&rft.date=1997-05-01&rft.volume=50&rft.issue=5&rft.spage=442&rft.epage=444&rft.pages=442-444&rft.issn=0021-9746&rft.eissn=1472-4146&rft.coden=JCPAAK&rft_id=info:doi/10.1136/jcp.50.5.442&rft_dat=%3Cproquest_pubme%3E3971438311%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1770458419&rft_id=info:pmid/9215133&rfr_iscdi=true |