Increased Intestinal Microbial Diversity Following Fecal Microbiota Transplant for Active Crohn's Disease

The microbiota in the lumen of patients with Crohn's disease (CD) is characterized by reduced diversity, particularly Firmicutes and Bacteroidetes. It is unknown whether the introduction of the intestinal microbiota from healthy individuals could correct this dysbiosis and reverse mucosal infla...

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Veröffentlicht in:	Inflammatory bowel diseases 2016-09, Vol.22 (9), p.2182-2190
Hauptverfasser:	Vaughn, Byron P, Vatanen, Tommi, Allegretti, Jessica R, Bai, Aiping, Xavier, Ramnik J, Korzenik, Joshua, Gevers, Dirk, Ting, Amanda, Robson, Simon C, Moss, Alan C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Crohn Disease - microbiology Crohn Disease - therapy Donor Selection Dysbiosis - therapy Fecal Microbiota Transplantation Feces - microbiology Female Firmicutes Gastrointestinal Microbiome Humans Intestinal Mucosa - immunology Intestines - microbiology Male Metabolic Networks and Pathways Middle Aged Prospective Studies Remission Induction T-Lymphocytes - classification United States Whole Genome Sequencing Young Adult
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