Modulating In Vivo Degradation Rate of Injectable Extracellular Matrix Hydrogels

Extracellular matrix (ECM) derived hydrogels are increasingly used as scaffolds to stimulate endogenous repair. However, few studies have examined how altering the degradation rates of these materials affect cellular interaction . This study sought to examine how crosslinking or matrix metalloprotei...

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Veröffentlicht in:	Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2016-04, Vol.4 (16), p.2794-2802
Hauptverfasser:	Wassenaar, Jean W, Braden, Rebecca L, Osborn, Kent G, Christman, Karen L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biology cross-linking reagents Crosslinking Degradation doxycycline Electrochemical machining extracellular matrix Hydrogels In vivo methods and tests Matrix metalloproteinases mechanical properties metalloproteinases myocardium swine
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