Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin‐binding geometry hypothesis

Versions of a previously discovered β‐hairpin peptide inhibitor of IAPP aggregation that are stabilized in that conformation, or even forced to remain in the hairpin conformation by a backbone cyclization constraint, display superior activity as inhibitors. The cyclized hairpin, cyclo‐WW2, displays...

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