Loss of SOCS3 in myeloid cells prolongs survival in a syngeneic model of glioma

In glioma, microglia and macrophages are the largest population of tumor-infiltrating cells, referred to as glioma associated macrophages (GAMs). Herein, we sought to determine the role of Suppressor of Cytokine Signaling 3 (SOCS3), a negative regulator of Signal Transducer and Activator of Transcri...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oncotarget 2016-04, Vol.7 (15), p.20621-20635
Hauptverfasser:	McFarland, Braden C, Marks, Margaret P, Rowse, Amber L, Fehling, Samuel C, Gerigk, Magda, Qin, Hongwei, Benveniste, Etty N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Brain Neoplasms - genetics Brain Neoplasms - immunology Brain Neoplasms - pathology Cell Proliferation Glioma - genetics Glioma - immunology Glioma - pathology Mice Mice, Knockout Myeloid Cells - immunology Myeloid Cells - metabolism Myeloid Cells - pathology Research Paper Suppressor of Cytokine Signaling 3 Protein - physiology T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism T-Lymphocytes, Regulatory - pathology Tumor Cells, Cultured Tumor Microenvironment - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!