Granulocyte transfusions in hematologic malignancy patients with invasive pulmonary aspergillosis: outcomes and complications

Granulocyte transfusions (GTXs) have been used successfully as an adjunctive treatment option for invasive infections in some neutropenic patients with underlying hematologic malignancy (HM). We sought to determine the impact of GTX as an adjunct to antifungal therapy in 128 patients with HM and pro...

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Veröffentlicht in:	Annals of oncology 2013-07, Vol.24 (7), p.1873-1879
Hauptverfasser:	Raad, I.I., Chaftari, A.M., Al Shuaibi, M.M., Jiang, Y., Shomali, W., Cortes, J.E., Lichtiger, B., Hachem, R.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antifungal Agents - therapeutic use Antineoplastic agents aspergillosis Aspergillus Biological and medical sciences Cell Transplantation - adverse effects Child Female granulocyte transfusions Granulocytes - transplantation hematologic malignancy Human mycoses Humans Infectious diseases Invasive Pulmonary Aspergillosis - etiology Invasive Pulmonary Aspergillosis - mortality Invasive Pulmonary Aspergillosis - therapy Leukemia - complications Leukemia - mortality Lymphoma - complications Lymphoma - mortality Male Medical sciences Middle Aged Multivariate Analysis Mycoses Mycoses of the respiratory system Neutropenia - complications Neutropenia - mortality Original Pharmacology. Drug treatments Retrospective Studies Treatment Outcome Young Adult
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