Adverse Outcomes to Early Middle Age Linked With Childhood Residential Mobility

Introduction Links between childhood residential mobility and multiple adverse outcomes through to maturity, and effect modification of these associations by familial SES, are incompletely understood. Methods A national cohort of people born in Denmark in 1971–1997 were followed from their 15th birt...

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Veröffentlicht in:American journal of preventive medicine 2016-09, Vol.51 (3), p.291-300
Hauptverfasser: Webb, Roger T., PhD, Pedersen, Carsten B., DrMedSc, Mok, Pearl L.H., PhD
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creator Webb, Roger T., PhD
Pedersen, Carsten B., DrMedSc
Mok, Pearl L.H., PhD
description Introduction Links between childhood residential mobility and multiple adverse outcomes through to maturity, and effect modification of these associations by familial SES, are incompletely understood. Methods A national cohort of people born in Denmark in 1971–1997 were followed from their 15th birthdays until their early forties (N=1,475,030). Residential moves during each age year between birth and age 14 years were examined, with follow-up to 2013. Incidence rate ratios for attempted suicide, violent criminality, psychiatric illness, substance misuse, and natural and unnatural deaths were estimated. The analyses were conducted during 2014–2015. Results Elevated risks were observed for all examined outcomes, with excess risk seen among those exposed to multiple versus single relocations in a year. Risks grew incrementally with increasing age of exposure to mobility. For violent offending, attempted suicide, substance misuse, and unnatural death, sharp spikes in risk linked with multiple relocations in a year during early/mid-adolescence were found. With attempted suicide and violent offending, the primary outcomes, a distinct risk gradient was observed with increasing age at exposure across the socioeconomic spectrum. Conclusions The links between childhood residential mobility and negative outcomes in later life appear widespread across multiple endpoints, with elevation in risk being particularly marked if frequent residential change occurs during early/mid-adolescence. Heightened vigilance is indicated for relocated adolescents and their families, with a view to preventing longer-term adverse outcomes in this population among all socioeconomic groups. Risk management will require close cooperation among multiple public agencies, particularly child, adolescent, and adult mental health services.
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Methods A national cohort of people born in Denmark in 1971–1997 were followed from their 15th birthdays until their early forties (N=1,475,030). Residential moves during each age year between birth and age 14 years were examined, with follow-up to 2013. Incidence rate ratios for attempted suicide, violent criminality, psychiatric illness, substance misuse, and natural and unnatural deaths were estimated. The analyses were conducted during 2014–2015. Results Elevated risks were observed for all examined outcomes, with excess risk seen among those exposed to multiple versus single relocations in a year. Risks grew incrementally with increasing age of exposure to mobility. For violent offending, attempted suicide, substance misuse, and unnatural death, sharp spikes in risk linked with multiple relocations in a year during early/mid-adolescence were found. With attempted suicide and violent offending, the primary outcomes, a distinct risk gradient was observed with increasing age at exposure across the socioeconomic spectrum. Conclusions The links between childhood residential mobility and negative outcomes in later life appear widespread across multiple endpoints, with elevation in risk being particularly marked if frequent residential change occurs during early/mid-adolescence. Heightened vigilance is indicated for relocated adolescents and their families, with a view to preventing longer-term adverse outcomes in this population among all socioeconomic groups. Risk management will require close cooperation among multiple public agencies, particularly child, adolescent, and adult mental health services.</description><identifier>ISSN: 0749-3797</identifier><identifier>EISSN: 1873-2607</identifier><identifier>DOI: 10.1016/j.amepre.2016.04.011</identifier><identifier>PMID: 27288289</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Cohort Studies ; Criminal Behavior ; Denmark - epidemiology ; Female ; Humans ; Internal Medicine ; Longitudinal Studies ; Male ; Mental Disorders - epidemiology ; Mental Disorders - etiology ; Population Dynamics - statistics &amp; numerical data ; Registries - statistics &amp; numerical data ; Risk Factors ; Social Class ; Substance-Related Disorders - epidemiology ; Substance-Related Disorders - etiology ; Suicide, Attempted - statistics &amp; numerical data</subject><ispartof>American journal of preventive medicine, 2016-09, Vol.51 (3), p.291-300</ispartof><rights>American Journal of Preventive Medicine</rights><rights>2016 American Journal of Preventive Medicine</rights><rights>Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.</rights><rights>2016 Elsevier Inc. on behalf of American Journal of Preventive Medicine. All rights reserved. 2016 American Journal of Preventive Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c518t-cbfb41628fa2a996ae7922ece3a1a7760ad080abef5fa25d22e425afde5398133</citedby><cites>FETCH-LOGICAL-c518t-cbfb41628fa2a996ae7922ece3a1a7760ad080abef5fa25d22e425afde5398133</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0749379716301180$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27288289$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Webb, Roger T., PhD</creatorcontrib><creatorcontrib>Pedersen, Carsten B., DrMedSc</creatorcontrib><creatorcontrib>Mok, Pearl L.H., PhD</creatorcontrib><title>Adverse Outcomes to Early Middle Age Linked With Childhood Residential Mobility</title><title>American journal of preventive medicine</title><addtitle>Am J Prev Med</addtitle><description>Introduction Links between childhood residential mobility and multiple adverse outcomes through to maturity, and effect modification of these associations by familial SES, are incompletely understood. Methods A national cohort of people born in Denmark in 1971–1997 were followed from their 15th birthdays until their early forties (N=1,475,030). Residential moves during each age year between birth and age 14 years were examined, with follow-up to 2013. Incidence rate ratios for attempted suicide, violent criminality, psychiatric illness, substance misuse, and natural and unnatural deaths were estimated. The analyses were conducted during 2014–2015. Results Elevated risks were observed for all examined outcomes, with excess risk seen among those exposed to multiple versus single relocations in a year. Risks grew incrementally with increasing age of exposure to mobility. For violent offending, attempted suicide, substance misuse, and unnatural death, sharp spikes in risk linked with multiple relocations in a year during early/mid-adolescence were found. With attempted suicide and violent offending, the primary outcomes, a distinct risk gradient was observed with increasing age at exposure across the socioeconomic spectrum. Conclusions The links between childhood residential mobility and negative outcomes in later life appear widespread across multiple endpoints, with elevation in risk being particularly marked if frequent residential change occurs during early/mid-adolescence. Heightened vigilance is indicated for relocated adolescents and their families, with a view to preventing longer-term adverse outcomes in this population among all socioeconomic groups. Risk management will require close cooperation among multiple public agencies, particularly child, adolescent, and adult mental health services.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Cohort Studies</subject><subject>Criminal Behavior</subject><subject>Denmark - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Mental Disorders - epidemiology</subject><subject>Mental Disorders - etiology</subject><subject>Population Dynamics - statistics &amp; numerical data</subject><subject>Registries - statistics &amp; numerical data</subject><subject>Risk Factors</subject><subject>Social Class</subject><subject>Substance-Related Disorders - epidemiology</subject><subject>Substance-Related Disorders - etiology</subject><subject>Suicide, Attempted - statistics &amp; numerical data</subject><issn>0749-3797</issn><issn>1873-2607</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUk1v1DAQtRAV3Rb-AUI-ckmwnQ87F6TVqqVIW61UQBwtx550vXXixU5W2n-Poy2F9sLJsua9N2_mDULvKckpofWnXa562AfIWfrlpMwJpa_QggpeZKwm_DVaEF42WcEbfo4uYtwRQrigzRt0zjgTgolmgTZLc4AQAW-mUfseIh49vlLBHfGtNcYBXt4DXtvhAQz-acctXm2tM1vvDb6DaA0Mo1UO3_rWOjse36KzTrkI7x7fS_Tj-ur76iZbb758XS3Xma6oGDPddm1JayY6xVTT1Ap4wxhoKBRVnNdEGSKIaqGrEqIyqVaySnUGqqIRtCgu0eeT7n5qezA62QjKyX2wvQpH6ZWVzyuD3cp7f5BlIxivZoGPjwLB_5ogjrK3UYNzagA_RUlTl-RP0CpByxNUBx9jgO6pDSVyzkLu5CkLOWchSSlTFon24V-LT6Q_y_87A6RFHSwEGbWFQYOxAfQojbf_6_BSQDs7WK3cAxwh7vwUhhSCpDIySeS3-R7mc6B1keiCFL8Btjmy4A</recordid><startdate>20160901</startdate><enddate>20160901</enddate><creator>Webb, Roger T., PhD</creator><creator>Pedersen, Carsten B., DrMedSc</creator><creator>Mok, Pearl L.H., PhD</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160901</creationdate><title>Adverse Outcomes to Early Middle Age Linked With Childhood Residential Mobility</title><author>Webb, Roger T., PhD ; Pedersen, Carsten B., DrMedSc ; Mok, Pearl L.H., PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c518t-cbfb41628fa2a996ae7922ece3a1a7760ad080abef5fa25d22e425afde5398133</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Cohort Studies</topic><topic>Criminal Behavior</topic><topic>Denmark - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Mental Disorders - epidemiology</topic><topic>Mental Disorders - etiology</topic><topic>Population Dynamics - statistics &amp; numerical data</topic><topic>Registries - statistics &amp; numerical data</topic><topic>Risk Factors</topic><topic>Social Class</topic><topic>Substance-Related Disorders - epidemiology</topic><topic>Substance-Related Disorders - etiology</topic><topic>Suicide, Attempted - statistics &amp; numerical data</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Webb, Roger T., PhD</creatorcontrib><creatorcontrib>Pedersen, Carsten B., DrMedSc</creatorcontrib><creatorcontrib>Mok, Pearl L.H., PhD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of preventive medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Webb, Roger T., PhD</au><au>Pedersen, Carsten B., DrMedSc</au><au>Mok, Pearl L.H., PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adverse Outcomes to Early Middle Age Linked With Childhood Residential Mobility</atitle><jtitle>American journal of preventive medicine</jtitle><addtitle>Am J Prev Med</addtitle><date>2016-09-01</date><risdate>2016</risdate><volume>51</volume><issue>3</issue><spage>291</spage><epage>300</epage><pages>291-300</pages><issn>0749-3797</issn><eissn>1873-2607</eissn><abstract>Introduction Links between childhood residential mobility and multiple adverse outcomes through to maturity, and effect modification of these associations by familial SES, are incompletely understood. Methods A national cohort of people born in Denmark in 1971–1997 were followed from their 15th birthdays until their early forties (N=1,475,030). Residential moves during each age year between birth and age 14 years were examined, with follow-up to 2013. Incidence rate ratios for attempted suicide, violent criminality, psychiatric illness, substance misuse, and natural and unnatural deaths were estimated. The analyses were conducted during 2014–2015. Results Elevated risks were observed for all examined outcomes, with excess risk seen among those exposed to multiple versus single relocations in a year. Risks grew incrementally with increasing age of exposure to mobility. For violent offending, attempted suicide, substance misuse, and unnatural death, sharp spikes in risk linked with multiple relocations in a year during early/mid-adolescence were found. With attempted suicide and violent offending, the primary outcomes, a distinct risk gradient was observed with increasing age at exposure across the socioeconomic spectrum. Conclusions The links between childhood residential mobility and negative outcomes in later life appear widespread across multiple endpoints, with elevation in risk being particularly marked if frequent residential change occurs during early/mid-adolescence. Heightened vigilance is indicated for relocated adolescents and their families, with a view to preventing longer-term adverse outcomes in this population among all socioeconomic groups. Risk management will require close cooperation among multiple public agencies, particularly child, adolescent, and adult mental health services.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>27288289</pmid><doi>10.1016/j.amepre.2016.04.011</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
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subjects Adolescent
Adult
Age Factors
Cohort Studies
Criminal Behavior
Denmark - epidemiology
Female
Humans
Internal Medicine
Longitudinal Studies
Male
Mental Disorders - epidemiology
Mental Disorders - etiology
Population Dynamics - statistics & numerical data
Registries - statistics & numerical data
Risk Factors
Social Class
Substance-Related Disorders - epidemiology
Substance-Related Disorders - etiology
Suicide, Attempted - statistics & numerical data
title Adverse Outcomes to Early Middle Age Linked With Childhood Residential Mobility
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