Dexamethasone and High-Dose Methotrexate Improve Outcome for Children and Young Adults With High-Risk B-Acute Lymphoblastic Leukemia: A Report From Children's Oncology Group Study AALL0232

Survival for children and young adults with high-risk B-acute lymphoblastic leukemia has improved significantly, but 20% to 25% of patients are not cured. Children's Oncology Group study AALL0232 tested two interventions to improve survival. Between January 2004 and January 2011, AALL0232 enrol...

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Veröffentlicht in:	Journal of clinical oncology 2016-07, Vol.34 (20), p.2380-2388
Hauptverfasser:	Larsen, Eric C, Devidas, Meenakshi, Chen, Si, Salzer, Wanda L, Raetz, Elizabeth A, Loh, Mignon L, Mattano, Jr, Leonard A, Cole, Catherine, Eicher, Alisa, Haugan, Maureen, Sorenson, Mark, Heerema, Nyla A, Carroll, Andrew A, Gastier-Foster, Julie M, Borowitz, Michael J, Wood, Brent L, Willman, Cheryl L, Winick, Naomi J, Hunger, Stephen P, Carroll, William L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Child Child, Preschool Dexamethasone - administration & dosage Dexamethasone - adverse effects Female Humans Infant Male Methotrexate - administration & dosage Methotrexate - adverse effects ORIGINAL REPORTS Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality Young Adult
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