Determinants and Consequences of Obesity

To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity. Narrative review of the publications of the NHS and NHS II between 1976 and 2016. Long-term NHS research has shown that weight gain and bein...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:American journal of public health (1971) 2016-09, Vol.106 (9), p.1656-1662
Hauptverfasser: Hruby, Adela, Manson, JoAnn E, Qi, Lu, Malik, Vasanti S, Rimm, Eric B, Sun, Qi, Willett, Walter C, Hu, Frank B
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1662
container_issue 9
container_start_page 1656
container_title American journal of public health (1971)
container_volume 106
creator Hruby, Adela
Manson, JoAnn E
Qi, Lu
Malik, Vasanti S
Rimm, Eric B
Sun, Qi
Willett, Walter C
Hu, Frank B
description To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity. Narrative review of the publications of the NHS and NHS II between 1976 and 2016. Long-term NHS research has shown that weight gain and being overweight or obese are important risk factors for type 2 diabetes, cardiovascular diseases, certain types of cancers, and premature death. The cohorts have elucidated the role of dietary and lifestyle factors in obesity, especially sugar-sweetened beverages, poor diet quality, physical inactivity, prolonged screen time, short sleep duration or shift work, and built environment characteristics. Genome-wide association and gene-lifestyle interaction studies have shown that genetic factors predispose individuals to obesity but that such susceptibility can be attenuated by healthy lifestyle choices. This research has contributed to evolving clinical and public health guidelines on the importance of limiting weight gain through healthy dietary and lifestyle behaviors. The NHS cohorts have contributed to our understanding of the risk factors for and consequences of obesity and made a lasting impact on clinical and public health guidelines on obesity prevention.
doi_str_mv 10.2105/AJPH.2016.303326
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981805</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4155283401</sourcerecordid><originalsourceid>FETCH-LOGICAL-c537t-9ea71fcd7baadf6974ed6b264a5cb94d6f7cbf0d084d1cb7a4e36d40032eb8ee3</originalsourceid><addsrcrecordid>eNpdkc1Lw0AQxRdRbK3ePUnBSy-psx_ZZC9CqR9VCvWg52WzO9GUdlOzidD_3oTWop5mYH7zmDePkEsKY0Yhvpk8v8zGDKgcc-CcySPSp7GgEYBIj0kfQEHbc9kjZyEsAShVMT0lPZaIWAkJfTK6wxqrdeGNr8PQeDeclj7gZ4PeYhiW-XCRYSjq7Tk5yc0q4MW-Dsjbw_3rdBbNF49P08k8sjFP6kihSWhuXZIZ43KpEoFOZkwKE9tMCSfzxGY5OEiFozZLjEAunWiPZJiliHxAbne6myZbo7Po68qs9KYq1qba6tIU-u_EFx_6vfzSQqU0hbgVGO0FqrK1EWq9LoLF1cp4LJugaUopU0ymskWv_6HLsql8a6-jOLBUSNVSsKNsVYZQYX44hoLuYtBdDLqLQe9iaFeufps4LPz8nX8DdQmDWA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1813028469</pqid></control><display><type>article</type><title>Determinants and Consequences of Obesity</title><source>MEDLINE</source><source>PAIS Index</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>EBSCOhost Business Source Complete</source><creator>Hruby, Adela ; Manson, JoAnn E ; Qi, Lu ; Malik, Vasanti S ; Rimm, Eric B ; Sun, Qi ; Willett, Walter C ; Hu, Frank B</creator><creatorcontrib>Hruby, Adela ; Manson, JoAnn E ; Qi, Lu ; Malik, Vasanti S ; Rimm, Eric B ; Sun, Qi ; Willett, Walter C ; Hu, Frank B</creatorcontrib><description>To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity. Narrative review of the publications of the NHS and NHS II between 1976 and 2016. Long-term NHS research has shown that weight gain and being overweight or obese are important risk factors for type 2 diabetes, cardiovascular diseases, certain types of cancers, and premature death. The cohorts have elucidated the role of dietary and lifestyle factors in obesity, especially sugar-sweetened beverages, poor diet quality, physical inactivity, prolonged screen time, short sleep duration or shift work, and built environment characteristics. Genome-wide association and gene-lifestyle interaction studies have shown that genetic factors predispose individuals to obesity but that such susceptibility can be attenuated by healthy lifestyle choices. This research has contributed to evolving clinical and public health guidelines on the importance of limiting weight gain through healthy dietary and lifestyle behaviors. The NHS cohorts have contributed to our understanding of the risk factors for and consequences of obesity and made a lasting impact on clinical and public health guidelines on obesity prevention.</description><identifier>ISSN: 0090-0036</identifier><identifier>EISSN: 1541-0048</identifier><identifier>DOI: 10.2105/AJPH.2016.303326</identifier><identifier>PMID: 27459460</identifier><identifier>CODEN: AJPHDS</identifier><language>eng</language><publisher>United States: American Public Health Association</publisher><subject>Adult ; AJPH Special Section: NHS Contributions ; Beverages ; Body mass index ; Built environment ; Cardiovascular diseases ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - etiology ; Chronic Disease ; Chronic illnesses ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetes Mellitus, Type 2 - etiology ; Diet ; Epidemiologic Studies ; Exercise/Physical Activity ; Female ; Fruit juices ; Genetic factors ; Genetics ; Grain ; Health care ; Health risk assessment ; Humans ; Life Style ; Lifestyles ; Longitudinal Studies ; Middle age ; Middle Aged ; Mortality ; Mortality, Premature ; Neoplasms - epidemiology ; Neoplasms - etiology ; Nurses ; Nutrition/Food ; Nuts ; Obesity ; Obesity - complications ; Obesity - epidemiology ; Obesity/Overweight/Underweight ; Oils &amp; fats ; Overweight ; Prevention ; Prospective Studies ; Public health ; Questionnaires ; Risk Factors ; Sedentary Lifestyle ; Self report ; Shift work ; Studies ; United States - epidemiology ; Urban environments ; Weight control ; Women's Health ; Womens health ; Working conditions</subject><ispartof>American journal of public health (1971), 2016-09, Vol.106 (9), p.1656-1662</ispartof><rights>Copyright American Public Health Association Sep 2016</rights><rights>American Public Health Association 2016 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c537t-9ea71fcd7baadf6974ed6b264a5cb94d6f7cbf0d084d1cb7a4e36d40032eb8ee3</citedby><cites>FETCH-LOGICAL-c537t-9ea71fcd7baadf6974ed6b264a5cb94d6f7cbf0d084d1cb7a4e36d40032eb8ee3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981805/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981805/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27843,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27459460$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hruby, Adela</creatorcontrib><creatorcontrib>Manson, JoAnn E</creatorcontrib><creatorcontrib>Qi, Lu</creatorcontrib><creatorcontrib>Malik, Vasanti S</creatorcontrib><creatorcontrib>Rimm, Eric B</creatorcontrib><creatorcontrib>Sun, Qi</creatorcontrib><creatorcontrib>Willett, Walter C</creatorcontrib><creatorcontrib>Hu, Frank B</creatorcontrib><title>Determinants and Consequences of Obesity</title><title>American journal of public health (1971)</title><addtitle>Am J Public Health</addtitle><description>To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity. Narrative review of the publications of the NHS and NHS II between 1976 and 2016. Long-term NHS research has shown that weight gain and being overweight or obese are important risk factors for type 2 diabetes, cardiovascular diseases, certain types of cancers, and premature death. The cohorts have elucidated the role of dietary and lifestyle factors in obesity, especially sugar-sweetened beverages, poor diet quality, physical inactivity, prolonged screen time, short sleep duration or shift work, and built environment characteristics. Genome-wide association and gene-lifestyle interaction studies have shown that genetic factors predispose individuals to obesity but that such susceptibility can be attenuated by healthy lifestyle choices. This research has contributed to evolving clinical and public health guidelines on the importance of limiting weight gain through healthy dietary and lifestyle behaviors. The NHS cohorts have contributed to our understanding of the risk factors for and consequences of obesity and made a lasting impact on clinical and public health guidelines on obesity prevention.</description><subject>Adult</subject><subject>AJPH Special Section: NHS Contributions</subject><subject>Beverages</subject><subject>Body mass index</subject><subject>Built environment</subject><subject>Cardiovascular diseases</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Chronic Disease</subject><subject>Chronic illnesses</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - etiology</subject><subject>Diet</subject><subject>Epidemiologic Studies</subject><subject>Exercise/Physical Activity</subject><subject>Female</subject><subject>Fruit juices</subject><subject>Genetic factors</subject><subject>Genetics</subject><subject>Grain</subject><subject>Health care</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Life Style</subject><subject>Lifestyles</subject><subject>Longitudinal Studies</subject><subject>Middle age</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Mortality, Premature</subject><subject>Neoplasms - epidemiology</subject><subject>Neoplasms - etiology</subject><subject>Nurses</subject><subject>Nutrition/Food</subject><subject>Nuts</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Obesity - epidemiology</subject><subject>Obesity/Overweight/Underweight</subject><subject>Oils &amp; fats</subject><subject>Overweight</subject><subject>Prevention</subject><subject>Prospective Studies</subject><subject>Public health</subject><subject>Questionnaires</subject><subject>Risk Factors</subject><subject>Sedentary Lifestyle</subject><subject>Self report</subject><subject>Shift work</subject><subject>Studies</subject><subject>United States - epidemiology</subject><subject>Urban environments</subject><subject>Weight control</subject><subject>Women's Health</subject><subject>Womens health</subject><subject>Working conditions</subject><issn>0090-0036</issn><issn>1541-0048</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7TQ</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkc1Lw0AQxRdRbK3ePUnBSy-psx_ZZC9CqR9VCvWg52WzO9GUdlOzidD_3oTWop5mYH7zmDePkEsKY0Yhvpk8v8zGDKgcc-CcySPSp7GgEYBIj0kfQEHbc9kjZyEsAShVMT0lPZaIWAkJfTK6wxqrdeGNr8PQeDeclj7gZ4PeYhiW-XCRYSjq7Tk5yc0q4MW-Dsjbw_3rdBbNF49P08k8sjFP6kihSWhuXZIZ43KpEoFOZkwKE9tMCSfzxGY5OEiFozZLjEAunWiPZJiliHxAbne6myZbo7Po68qs9KYq1qba6tIU-u_EFx_6vfzSQqU0hbgVGO0FqrK1EWq9LoLF1cp4LJugaUopU0ymskWv_6HLsql8a6-jOLBUSNVSsKNsVYZQYX44hoLuYtBdDLqLQe9iaFeufps4LPz8nX8DdQmDWA</recordid><startdate>201609</startdate><enddate>201609</enddate><creator>Hruby, Adela</creator><creator>Manson, JoAnn E</creator><creator>Qi, Lu</creator><creator>Malik, Vasanti S</creator><creator>Rimm, Eric B</creator><creator>Sun, Qi</creator><creator>Willett, Walter C</creator><creator>Hu, Frank B</creator><general>American Public Health Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>0U~</scope><scope>1-H</scope><scope>3V.</scope><scope>7RV</scope><scope>7TQ</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88A</scope><scope>88C</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>88J</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DHY</scope><scope>DON</scope><scope>DPSOV</scope><scope>DWQXO</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>KC-</scope><scope>L.-</scope><scope>L.0</scope><scope>LK8</scope><scope>M0C</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2L</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M2R</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>PYCSY</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201609</creationdate><title>Determinants and Consequences of Obesity</title><author>Hruby, Adela ; Manson, JoAnn E ; Qi, Lu ; Malik, Vasanti S ; Rimm, Eric B ; Sun, Qi ; Willett, Walter C ; Hu, Frank B</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c537t-9ea71fcd7baadf6974ed6b264a5cb94d6f7cbf0d084d1cb7a4e36d40032eb8ee3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>AJPH Special Section: NHS Contributions</topic><topic>Beverages</topic><topic>Body mass index</topic><topic>Built environment</topic><topic>Cardiovascular diseases</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Chronic Disease</topic><topic>Chronic illnesses</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - etiology</topic><topic>Diet</topic><topic>Epidemiologic Studies</topic><topic>Exercise/Physical Activity</topic><topic>Female</topic><topic>Fruit juices</topic><topic>Genetic factors</topic><topic>Genetics</topic><topic>Grain</topic><topic>Health care</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Life Style</topic><topic>Lifestyles</topic><topic>Longitudinal Studies</topic><topic>Middle age</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Mortality, Premature</topic><topic>Neoplasms - epidemiology</topic><topic>Neoplasms - etiology</topic><topic>Nurses</topic><topic>Nutrition/Food</topic><topic>Nuts</topic><topic>Obesity</topic><topic>Obesity - complications</topic><topic>Obesity - epidemiology</topic><topic>Obesity/Overweight/Underweight</topic><topic>Oils &amp; fats</topic><topic>Overweight</topic><topic>Prevention</topic><topic>Prospective Studies</topic><topic>Public health</topic><topic>Questionnaires</topic><topic>Risk Factors</topic><topic>Sedentary Lifestyle</topic><topic>Self report</topic><topic>Shift work</topic><topic>Studies</topic><topic>United States - epidemiology</topic><topic>Urban environments</topic><topic>Weight control</topic><topic>Women's Health</topic><topic>Womens health</topic><topic>Working conditions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hruby, Adela</creatorcontrib><creatorcontrib>Manson, JoAnn E</creatorcontrib><creatorcontrib>Qi, Lu</creatorcontrib><creatorcontrib>Malik, Vasanti S</creatorcontrib><creatorcontrib>Rimm, Eric B</creatorcontrib><creatorcontrib>Sun, Qi</creatorcontrib><creatorcontrib>Willett, Walter C</creatorcontrib><creatorcontrib>Hu, Frank B</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>Global News &amp; ABI/Inform Professional</collection><collection>Trade PRO</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>PAIS Index</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>PAIS International</collection><collection>PAIS International (Ovid)</collection><collection>Politics Collection</collection><collection>ProQuest Central Korea</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Politics Collection</collection><collection>ABI/INFORM Professional Advanced</collection><collection>ABI/INFORM Professional Standard</collection><collection>ProQuest Biological Science Collection</collection><collection>ABI/INFORM Global</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Political Science Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Social Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Environmental Science Database</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>Environmental Science Collection</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of public health (1971)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hruby, Adela</au><au>Manson, JoAnn E</au><au>Qi, Lu</au><au>Malik, Vasanti S</au><au>Rimm, Eric B</au><au>Sun, Qi</au><au>Willett, Walter C</au><au>Hu, Frank B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Determinants and Consequences of Obesity</atitle><jtitle>American journal of public health (1971)</jtitle><addtitle>Am J Public Health</addtitle><date>2016-09</date><risdate>2016</risdate><volume>106</volume><issue>9</issue><spage>1656</spage><epage>1662</epage><pages>1656-1662</pages><issn>0090-0036</issn><eissn>1541-0048</eissn><coden>AJPHDS</coden><abstract>To review the contribution of the Nurses' Health Studies (NHS and NHS II) in addressing hypotheses regarding risk factors for and consequences of obesity. Narrative review of the publications of the NHS and NHS II between 1976 and 2016. Long-term NHS research has shown that weight gain and being overweight or obese are important risk factors for type 2 diabetes, cardiovascular diseases, certain types of cancers, and premature death. The cohorts have elucidated the role of dietary and lifestyle factors in obesity, especially sugar-sweetened beverages, poor diet quality, physical inactivity, prolonged screen time, short sleep duration or shift work, and built environment characteristics. Genome-wide association and gene-lifestyle interaction studies have shown that genetic factors predispose individuals to obesity but that such susceptibility can be attenuated by healthy lifestyle choices. This research has contributed to evolving clinical and public health guidelines on the importance of limiting weight gain through healthy dietary and lifestyle behaviors. The NHS cohorts have contributed to our understanding of the risk factors for and consequences of obesity and made a lasting impact on clinical and public health guidelines on obesity prevention.</abstract><cop>United States</cop><pub>American Public Health Association</pub><pmid>27459460</pmid><doi>10.2105/AJPH.2016.303326</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0090-0036
ispartof American journal of public health (1971), 2016-09, Vol.106 (9), p.1656-1662
issn 0090-0036
1541-0048
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4981805
source MEDLINE; PAIS Index; PubMed Central; Alma/SFX Local Collection; EBSCOhost Business Source Complete
subjects Adult
AJPH Special Section: NHS Contributions
Beverages
Body mass index
Built environment
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Chronic Disease
Chronic illnesses
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - etiology
Diet
Epidemiologic Studies
Exercise/Physical Activity
Female
Fruit juices
Genetic factors
Genetics
Grain
Health care
Health risk assessment
Humans
Life Style
Lifestyles
Longitudinal Studies
Middle age
Middle Aged
Mortality
Mortality, Premature
Neoplasms - epidemiology
Neoplasms - etiology
Nurses
Nutrition/Food
Nuts
Obesity
Obesity - complications
Obesity - epidemiology
Obesity/Overweight/Underweight
Oils & fats
Overweight
Prevention
Prospective Studies
Public health
Questionnaires
Risk Factors
Sedentary Lifestyle
Self report
Shift work
Studies
United States - epidemiology
Urban environments
Weight control
Women's Health
Womens health
Working conditions
title Determinants and Consequences of Obesity
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T05%3A18%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Determinants%20and%20Consequences%20of%20Obesity&rft.jtitle=American%20journal%20of%20public%20health%20(1971)&rft.au=Hruby,%20Adela&rft.date=2016-09&rft.volume=106&rft.issue=9&rft.spage=1656&rft.epage=1662&rft.pages=1656-1662&rft.issn=0090-0036&rft.eissn=1541-0048&rft.coden=AJPHDS&rft_id=info:doi/10.2105/AJPH.2016.303326&rft_dat=%3Cproquest_pubme%3E4155283401%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1813028469&rft_id=info:pmid/27459460&rfr_iscdi=true