Leucine Zipper-bearing Kinase promotes axon growth in mammalian central nervous system neurons

Leucine Zipper-bearing Kinase (LZK/MAP3K13) is a member of the mixed lineage kinase family with high sequence identity to Dual Leucine Zipper Kinase (DLK/MAP3K12). While DLK is established as a key regulator of axonal responses to injury, the role of LZK in mammalian neurons is poorly understood. By...

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Veröffentlicht in:	Scientific reports 2016-08, Vol.6 (1), p.31482-31482, Article 31482
Hauptverfasser:	Chen, Meifan, Geoffroy, Cédric G., Wong, Hetty N., Tress, Oliver, Nguyen, Mallorie T., Holzman, Lawrence B., Jin, Yishi, Zheng, Binhai
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 631/378/1687 631/378/340 64/60 96/95 Animals Axons - physiology Cell Proliferation Cells, Cultured Central nervous system Central Nervous System - enzymology Gene Expression Gene Knockout Techniques Humanities and Social Sciences JNK protein Kinases Leucine zipper proteins Mammals MAP kinase MAP Kinase Kinase Kinases - genetics MAP Kinase Kinase Kinases - metabolism Mice multidisciplinary Neurons Next-generation sequencing Science Science (multidisciplinary)
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