Generating kidney tissue from pluripotent stem cells
With the isolation of human pluripotent stem cells came the possibility of generating specific cell types for regenerative medicine. This has required the development of protocols for directed differentiation into many distinct cell types. One of the more complicated tissue types to recreate is the...
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| Veröffentlicht in: | Cell death discovery 2016-07, Vol.2 (1), p.16053-16053, Article 16053 |
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| creator | Little, MH |
| description | With the isolation of human pluripotent stem cells came the possibility of generating specific cell types for regenerative medicine. This has required the development of protocols for directed differentiation into many distinct cell types. One of the more complicated tissue types to recreate is the kidney. Here we review recent progress towards the recreation of not only specific kidney cell types but complex kidney organoids, models of the developing human organ,
in vitro
. We will also discuss potential short and long term applications of these approaches. |
| doi_str_mv | 10.1038/cddiscovery.2016.53 |
| format | Article |
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in vitro
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in vitro
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| subjects | 631/532/2064/2158 692/699/1585 Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Cycle Analysis Life Sciences Review review-article Stem Cells |
| title | Generating kidney tissue from pluripotent stem cells |
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