OxyBS: estimation of 5-methylcytosine and 5-hydroxymethylcytosine from tandem-treated oxidative bisulfite and bisulfite DNA

The use of sodium bisulfite (BS) treatment followed by hybridization to an Illumina Infinium BeadChip (HumanMethylation450 and MethylationEPIC) is a common method for interrogating 5-methylcytosine (5mC) at single nucleotide resolution. However, standard treatment of DNA with BS does not allow disam...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2016-08, Vol.32 (16), p.2505-2507
Hauptverfasser:	Houseman, E Andres, Johnson, Kevin C, Christensen, Brock C
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Methylcytosine Applications Notes Cytosine DNA DNA Methylation Humans Likelihood Functions Microarray Analysis Sequence Analysis, DNA
Online-Zugang:	Volltext
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