The use of finger-stick blood to assess lactate in critically ill surgical patients
Abstract Background Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care...
Gespeichert in:
| Veröffentlicht in: | Annals of medicine and surgery 2016-09, Vol.10, p.41-48 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 48 |
|---|---|
| container_issue | |
| container_start_page | 41 |
| container_title | Annals of medicine and surgery |
| container_volume | 10 |
| creator | Sabat, Joseph Gould, Scott Gillego, Ezra Hariprashad, Anita Wiest, Christine Almonte, Shailyn Lucido, David J Gave, Asaf Leitman, I. Michael Eiref, Simon D |
| description | Abstract Background Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care unit, and to compare how capillary and arterial lactate trend over time in patients undergoing resuscitation for shock. Methods Capillary whole blood specimens were obtained from finger-sticks using a lancet, and assessed for lactate via a handheld point-of-care device as part of an “investigational use only” study. Comparison was made to arterial blood specimens that were assessed for lactate by standard laboratory reference methods. Results 40 patients (mean age 68, mean APACHEII 18, vasopressor use 62%) were included. The correlation between capillary and arterial lactate levels was 0.94 (p |
| doi_str_mv | 10.1016/j.amsu.2016.07.021 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4978218</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S2049080116300991</els_id><sourcerecordid>1813629055</sourcerecordid><originalsourceid>FETCH-LOGICAL-c580t-ec8e7845a126c417dccfebda414b0fb4eefa9f0e7af0161a58ecc1e8ce6f39e63</originalsourceid><addsrcrecordid>eNp9Uk1v1DAQjRCIVqV_gAPykUvCOJ-OhCqhCihSJQ4t55HjjLfeeuPFk1Taf4-jbavCgZPH8ntvxu9Nlr2XUEiQ7adtoXe8FGWqC-gKKOWr7LSEus9BgXz9oj7Jzpm3ACChqdpWvc1Oyq6pu6rvTrOb2zsSC5MIVlg3bSjmPDtzLwYfwijmIDQzMQuvzaxnEm4SJroE0d4fhPNe8BI361Xs9exomvld9sZqz3T-eJ5lv759vb28yq9_fv9x-eU6N42COSejqFN1o2XZmlp2ozGWhlHXsh7ADjWR1b0F6rRNn5S6UWSMJGWotVVPbXWWXRx198uwo9Gk3lF73Ee30_GAQTv8-2Vyd7gJD1j3nSqlSgIfHwVi-L0Qz7hzbMh7PVFYGKWSVVv20DQJWh6hJgbmSPa5jQRcA8EtroHgGghChymQRPrwcsBnypP9CfD5CKBk04OjiGyShYZGF8nMOAb3f_2Lf-jGu2nN4p4OxNuwxCkFgBK5RMCbdSXWjZBtBdD3svoDzMy0Ig</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1813629055</pqid></control><display><type>article</type><title>The use of finger-stick blood to assess lactate in critically ill surgical patients</title><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Sabat, Joseph ; Gould, Scott ; Gillego, Ezra ; Hariprashad, Anita ; Wiest, Christine ; Almonte, Shailyn ; Lucido, David J ; Gave, Asaf ; Leitman, I. Michael ; Eiref, Simon D</creator><creatorcontrib>Sabat, Joseph ; Gould, Scott ; Gillego, Ezra ; Hariprashad, Anita ; Wiest, Christine ; Almonte, Shailyn ; Lucido, David J ; Gave, Asaf ; Leitman, I. Michael ; Eiref, Simon D</creatorcontrib><description>Abstract Background Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care unit, and to compare how capillary and arterial lactate trend over time in patients undergoing resuscitation for shock. Methods Capillary whole blood specimens were obtained from finger-sticks using a lancet, and assessed for lactate via a handheld point-of-care device as part of an “investigational use only” study. Comparison was made to arterial blood specimens that were assessed for lactate by standard laboratory reference methods. Results 40 patients (mean age 68, mean APACHEII 18, vasopressor use 62%) were included. The correlation between capillary and arterial lactate levels was 0.94 (p < 0.001). Capillary lactate measured slightly higher on average than paired arterial values, with a mean difference 0.99 mmol/L. In patients being resuscitated for septic and hemorrhagic shock, capillary and arterial lactate trended closely over time: rising, peaking, and falling in tandem. Clearance of capillary and arterial lactate mirrored clinical improvement, normalizing in all patients except two that expired. Conclusion Finger-stick capillary lactate both correlates and trends closely with arterial lactate in critically ill surgical patients, undergoing resuscitation for shock.</description><identifier>ISSN: 2049-0801</identifier><identifier>EISSN: 2049-0801</identifier><identifier>DOI: 10.1016/j.amsu.2016.07.021</identifier><identifier>PMID: 27547397</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Capillary lactate ; Finger-stick ; Internal Medicine ; Original Research ; Point-of-care ; Shock ; Surgery</subject><ispartof>Annals of medicine and surgery, 2016-09, Vol.10, p.41-48</ispartof><rights>The Authors</rights><rights>2016 The Authors</rights><rights>2016 The Authors 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c580t-ec8e7845a126c417dccfebda414b0fb4eefa9f0e7af0161a58ecc1e8ce6f39e63</citedby><orcidid>0000-0001-7094-5657 ; 0000-0002-9671-8783</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978218/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978218/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27547397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sabat, Joseph</creatorcontrib><creatorcontrib>Gould, Scott</creatorcontrib><creatorcontrib>Gillego, Ezra</creatorcontrib><creatorcontrib>Hariprashad, Anita</creatorcontrib><creatorcontrib>Wiest, Christine</creatorcontrib><creatorcontrib>Almonte, Shailyn</creatorcontrib><creatorcontrib>Lucido, David J</creatorcontrib><creatorcontrib>Gave, Asaf</creatorcontrib><creatorcontrib>Leitman, I. Michael</creatorcontrib><creatorcontrib>Eiref, Simon D</creatorcontrib><title>The use of finger-stick blood to assess lactate in critically ill surgical patients</title><title>Annals of medicine and surgery</title><addtitle>Ann Med Surg (Lond)</addtitle><description>Abstract Background Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care unit, and to compare how capillary and arterial lactate trend over time in patients undergoing resuscitation for shock. Methods Capillary whole blood specimens were obtained from finger-sticks using a lancet, and assessed for lactate via a handheld point-of-care device as part of an “investigational use only” study. Comparison was made to arterial blood specimens that were assessed for lactate by standard laboratory reference methods. Results 40 patients (mean age 68, mean APACHEII 18, vasopressor use 62%) were included. The correlation between capillary and arterial lactate levels was 0.94 (p < 0.001). Capillary lactate measured slightly higher on average than paired arterial values, with a mean difference 0.99 mmol/L. In patients being resuscitated for septic and hemorrhagic shock, capillary and arterial lactate trended closely over time: rising, peaking, and falling in tandem. Clearance of capillary and arterial lactate mirrored clinical improvement, normalizing in all patients except two that expired. Conclusion Finger-stick capillary lactate both correlates and trends closely with arterial lactate in critically ill surgical patients, undergoing resuscitation for shock.</description><subject>Capillary lactate</subject><subject>Finger-stick</subject><subject>Internal Medicine</subject><subject>Original Research</subject><subject>Point-of-care</subject><subject>Shock</subject><subject>Surgery</subject><issn>2049-0801</issn><issn>2049-0801</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNp9Uk1v1DAQjRCIVqV_gAPykUvCOJ-OhCqhCihSJQ4t55HjjLfeeuPFk1Taf4-jbavCgZPH8ntvxu9Nlr2XUEiQ7adtoXe8FGWqC-gKKOWr7LSEus9BgXz9oj7Jzpm3ACChqdpWvc1Oyq6pu6rvTrOb2zsSC5MIVlg3bSjmPDtzLwYfwijmIDQzMQuvzaxnEm4SJroE0d4fhPNe8BI361Xs9exomvld9sZqz3T-eJ5lv759vb28yq9_fv9x-eU6N42COSejqFN1o2XZmlp2ozGWhlHXsh7ADjWR1b0F6rRNn5S6UWSMJGWotVVPbXWWXRx198uwo9Gk3lF73Ee30_GAQTv8-2Vyd7gJD1j3nSqlSgIfHwVi-L0Qz7hzbMh7PVFYGKWSVVv20DQJWh6hJgbmSPa5jQRcA8EtroHgGghChymQRPrwcsBnypP9CfD5CKBk04OjiGyShYZGF8nMOAb3f_2Lf-jGu2nN4p4OxNuwxCkFgBK5RMCbdSXWjZBtBdD3svoDzMy0Ig</recordid><startdate>20160901</startdate><enddate>20160901</enddate><creator>Sabat, Joseph</creator><creator>Gould, Scott</creator><creator>Gillego, Ezra</creator><creator>Hariprashad, Anita</creator><creator>Wiest, Christine</creator><creator>Almonte, Shailyn</creator><creator>Lucido, David J</creator><creator>Gave, Asaf</creator><creator>Leitman, I. Michael</creator><creator>Eiref, Simon D</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7094-5657</orcidid><orcidid>https://orcid.org/0000-0002-9671-8783</orcidid></search><sort><creationdate>20160901</creationdate><title>The use of finger-stick blood to assess lactate in critically ill surgical patients</title><author>Sabat, Joseph ; Gould, Scott ; Gillego, Ezra ; Hariprashad, Anita ; Wiest, Christine ; Almonte, Shailyn ; Lucido, David J ; Gave, Asaf ; Leitman, I. Michael ; Eiref, Simon D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c580t-ec8e7845a126c417dccfebda414b0fb4eefa9f0e7af0161a58ecc1e8ce6f39e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Capillary lactate</topic><topic>Finger-stick</topic><topic>Internal Medicine</topic><topic>Original Research</topic><topic>Point-of-care</topic><topic>Shock</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sabat, Joseph</creatorcontrib><creatorcontrib>Gould, Scott</creatorcontrib><creatorcontrib>Gillego, Ezra</creatorcontrib><creatorcontrib>Hariprashad, Anita</creatorcontrib><creatorcontrib>Wiest, Christine</creatorcontrib><creatorcontrib>Almonte, Shailyn</creatorcontrib><creatorcontrib>Lucido, David J</creatorcontrib><creatorcontrib>Gave, Asaf</creatorcontrib><creatorcontrib>Leitman, I. Michael</creatorcontrib><creatorcontrib>Eiref, Simon D</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Annals of medicine and surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sabat, Joseph</au><au>Gould, Scott</au><au>Gillego, Ezra</au><au>Hariprashad, Anita</au><au>Wiest, Christine</au><au>Almonte, Shailyn</au><au>Lucido, David J</au><au>Gave, Asaf</au><au>Leitman, I. Michael</au><au>Eiref, Simon D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The use of finger-stick blood to assess lactate in critically ill surgical patients</atitle><jtitle>Annals of medicine and surgery</jtitle><addtitle>Ann Med Surg (Lond)</addtitle><date>2016-09-01</date><risdate>2016</risdate><volume>10</volume><spage>41</spage><epage>48</epage><pages>41-48</pages><issn>2049-0801</issn><eissn>2049-0801</eissn><abstract>Abstract Background Using finger-stick capillary blood to assess lactate from the microcirculation may have utility in treating critically ill patients. Our goals were to determine how finger-stick capillary lactate correlates with arterial lactate levels in patients from the surgical intensive care unit, and to compare how capillary and arterial lactate trend over time in patients undergoing resuscitation for shock. Methods Capillary whole blood specimens were obtained from finger-sticks using a lancet, and assessed for lactate via a handheld point-of-care device as part of an “investigational use only” study. Comparison was made to arterial blood specimens that were assessed for lactate by standard laboratory reference methods. Results 40 patients (mean age 68, mean APACHEII 18, vasopressor use 62%) were included. The correlation between capillary and arterial lactate levels was 0.94 (p < 0.001). Capillary lactate measured slightly higher on average than paired arterial values, with a mean difference 0.99 mmol/L. In patients being resuscitated for septic and hemorrhagic shock, capillary and arterial lactate trended closely over time: rising, peaking, and falling in tandem. Clearance of capillary and arterial lactate mirrored clinical improvement, normalizing in all patients except two that expired. Conclusion Finger-stick capillary lactate both correlates and trends closely with arterial lactate in critically ill surgical patients, undergoing resuscitation for shock.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>27547397</pmid><doi>10.1016/j.amsu.2016.07.021</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-7094-5657</orcidid><orcidid>https://orcid.org/0000-0002-9671-8783</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2049-0801 |
| ispartof | Annals of medicine and surgery, 2016-09, Vol.10, p.41-48 |
| issn | 2049-0801 2049-0801 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4978218 |
| source | EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Capillary lactate Finger-stick Internal Medicine Original Research Point-of-care Shock Surgery |
| title | The use of finger-stick blood to assess lactate in critically ill surgical patients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T08%3A55%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20use%20of%20finger-stick%20blood%20to%20assess%20lactate%20in%20critically%20ill%20surgical%20patients&rft.jtitle=Annals%20of%20medicine%20and%20surgery&rft.au=Sabat,%20Joseph&rft.date=2016-09-01&rft.volume=10&rft.spage=41&rft.epage=48&rft.pages=41-48&rft.issn=2049-0801&rft.eissn=2049-0801&rft_id=info:doi/10.1016/j.amsu.2016.07.021&rft_dat=%3Cproquest_pubme%3E1813629055%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1813629055&rft_id=info:pmid/27547397&rft_els_id=S2049080116300991&rfr_iscdi=true |