Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding

Adiponectin regulates glucose and lipid metabolism, acting against metabolic syndrome and atherosclerosis. Accumulating evidence suggest that adiponectin acts on the brain including hypothalamic arcuate nucleus (ARC), where proopiomelanocortin (POMC) neurons play key roles in feeding regulation. Sev...

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Veröffentlicht in:	Scientific reports 2016-08, Vol.6 (1), p.30796, Article 30796
Hauptverfasser:	Suyama, Shigetomo, Maekawa, Fumihiko, Maejima, Yuko, Kubota, Naoto, Kadowaki, Takashi, Yada, Toshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1697/2601 631/443/319/1488/1562 64/60 9/74 Adiponectin Arcuate nucleus Arteriosclerosis Feeding Food Food intake Glucose Glucose metabolism Humanities and Social Sciences Hypothalamus Lipid metabolism Metabolic disorders Metabolic syndrome multidisciplinary Neurons Proopiomelanocortin Science
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