Estrogens, Neuroinflammation, and Neurodegeneration

Inflammatory activation of microglia is a hallmark of several disorders of the central nervous system. In addition to protecting the brain against inflammatory insults, microglia are neuroprotective and play a significant role in maintaining neuronal connectivity, but the prolongation of an inflamma...

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Veröffentlicht in:	Endocrine reviews 2016-08, Vol.37 (4), p.372-402
Hauptverfasser:	Villa, Alessandro, Vegeto, Elisabetta, Poletti, Angelo, Maggi, Adriana
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer's disease Animals Brain injury Cell activation Central nervous system Demyelinating Diseases - immunology Demyelinating Diseases - metabolism Disease control Estrogen receptors Estrogens Estrogens - metabolism Humans Hypoxia, Brain - immunology Hypoxia, Brain - metabolism Immune system Inflammation - immunology Inflammation - metabolism Inflammatory diseases Inflammatory response Microglia Microglia - immunology Microglia - metabolism Monocytes Movement disorders Multiple sclerosis Neural networks Neurodegenerative diseases Neurodegenerative Diseases - immunology Neurodegenerative Diseases - metabolism Neurological diseases Neuroprotection Parkinson's disease Prolongation Receptors Receptors, Estrogen - metabolism Reviews Sex Sex differences Stroke - immunology Stroke - metabolism
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