Quantitative assessment of the effects of water proton concentration and water T1 changes on amide proton transfer (APT) and nuclear overhauser enhancement (NOE) MRI: The origin of the APT imaging signal in brain tumor

Purpose To quantify pure chemical exchange–dependent saturation transfer (CEST) related amide proton transfer (APT) and nuclear Overhauser enhancement (NOE) signals in a rat glioma model and to investigate the mixed effects of water content and water T1 on APT and NOE imaging signals. Methods Eleven...

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Veröffentlicht in:	Magnetic resonance in medicine 2017-02, Vol.77 (2), p.855-863
Hauptverfasser:	Lee, Dong‐Hoon, Heo, Hye‐Young, Zhang, Kai, Zhang, Yi, Jiang, Shanshan, Zhao, Xuna, Zhou, Jinyuan
Format:	Artikel
Sprache:	eng
Schlagworte:	APT Brain Brain cancer Brain tumors CEST Glioma Magnetic resonance imaging Magnetization Medical imaging Moisture content Neuroimaging NOE Protons Reference signals Saturation Semisolids Tumors Water content water T1
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