Force Matters: Biomechanical Regulation of Cell Invasion and Migration in Disease

Atherosclerosis, cancer, and various chronic fibrotic conditions are characterized by an increase in the migratory behavior of resident cells and the enhanced invasion of assorted exogenous cells across a stiffened extracellular matrix (ECM). This stiffened scaffold aberrantly engages cellular mecha...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Trends in cell biology 2016-07, Vol.26 (7), p.486-497
Hauptverfasser:	Kai, FuiBoon, Laklai, Hanane, Weaver, Valerie M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomechanical Phenomena cancer cardiovascular disease Cell Movement Disease Extracellular Matrix - metabolism extracellular matrix stiffness fibrosis Humans invasion migration Neoplasm Invasiveness - pathology Pathology Podosomes - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!