Treatment of chronic hepatitis C with direct-acting antivirals: The role of resistance

The use of direct-acting antivirals(DAAs) to treat chronic hepatitis C has resulted in a significant increase in rates of sustained viral response(around 90%-95%) as compared with the standard treatment of peginterferon/ribavirin. Despite this, however, the rates of therapeutic failure in daily clin...

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Veröffentlicht in:	World journal of gastroenterology : WJG 2016-08, Vol.22 (29), p.6573-6581
Hauptverfasser:	Jiménez-Pérez, Miguel, González-Grande, Rocío, España Contreras, Pilar, Pinazo Martínez, Isabel, de la Cruz Lombardo, Jesús, Olmedo Martín, Raúl
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral Agents - therapeutic use antivirals Resistance Treatment Hepatitis Direct-acting Drug Resistance, Viral Hepacivirus - genetics Hepacivirus - physiology Hepatitis C, Chronic - drug therapy Humans Topic Highlight Treatment Failure Viral Nonstructural Proteins - antagonists & inhibitors virus
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