Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)

DMC1 is a recombinase that is essential for meiotic synapsis. Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of dmc1 in mice and human often leads to obstacles in spermatogenesis...

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Veröffentlicht in:	Scientific reports 2016-08, Vol.6 (1), p.30912-30912, Article 30912
Hauptverfasser:	Chen, Ji, Cui, Xiaojuan, Jia, Shaoting, Luo, Daji, Cao, Mengxi, Zhang, Yunsheng, Hu, Hongling, Huang, Kaiyao, Zhu, Zuoyan, Hu, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	13/2 13/31 14/19 14/28 14/32 14/63 38/91 631/136/2434/1822 631/80/641/1633 Animals DNA Repair Eukaryotes Fish Proteins - genetics Fish Proteins - metabolism Flagella Gene expression Gene Expression Profiling Humanities and Social Sciences Male Male sterility Meiosis Meiosis - physiology multidisciplinary Nuclei Oryzias - genetics Oryzias - growth & development Oryzias - metabolism Recombinase Recombinases - genetics Recombinases - metabolism Recombination Science Sperm Spermatogenesis Spermatogenesis - physiology Spermatozoa - metabolism Spermatozoa - pathology
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