Allosteric proteins as logarithmic sensors

Many sensory systems, from vision and hearing in animals to signal transduction in cells, respond to fold changes in signal relative to background. Responding to fold change requires that the system senses signal on a logarithmic scale, responding identically to a change in signal level from 1 to 3,...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2016-07, Vol.113 (30), p.E4423-E4430
Hauptverfasser:	Olsman, Noah, Goentoro, Lea
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Allosteric Regulation Animals Biological Sciences Feedback, Physiological Humans Mathematical models Models, Theoretical PNAS Plus Protein Conformation Proteins Proteins - chemistry Proteins - metabolism Sensors Signal Transduction
Online-Zugang:	Volltext
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