A sexually dimorphic effect of cholera toxin: rapid changes in colonic motility mediated via a 5‐HT3 receptor‐dependent pathway in female C57Bl/6 mice

Key points Cholera causes more than 100,000 deaths each year as a result of severe diarrhoea, vomiting and dehydration due to the actions of cholera toxin; more females than males are affected. Cholera toxin induces hypersecretion via release of mucosal serotonin and over‐activation of enteric neuro...

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Veröffentlicht in:The Journal of physiology 2016-08, Vol.594 (15), p.4325-4338
Hauptverfasser: Balasuriya, Gayathri K., Hill‐Yardin, Elisa L., Gershon, Michael D., Bornstein, Joel C.
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Sprache:eng
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