Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa

Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa

We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Genome announcements (Washington, DC) DC), 2016-07, Vol.4 (4)
Hauptverfasser: Mentoor, Juliet L D, Lubisi, Alison B, Gerdes, Truuska, Human, Stacey, Williams, June H, Venter, Marietjie
Format: Artikel
Sprache:eng
Schlagworte:
Viruses
West Nile virus
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 4
container_start_page
container_title Genome announcements (Washington, DC)
container_volume 4
creator Mentoor, Juliet L D
Lubisi, Alison B
Gerdes, Truuska
Human, Stacey
Williams, June H
Venter, Marietjie
description We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however, there are a lack of sequencing data from recent fatal cases in Southern Africa, where these strains likely originate. A better understanding of the genetic composition of highly neuroinvasive lineage 2 strains may facilitate the identification of putative genetic factors associated with increased virulence.
doi_str_mv 10.1128/genomea.00740-16
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966467</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1807892159</sourcerecordid><originalsourceid>FETCH-LOGICAL-c490t-1217b1b0b067fbb809bca0e8bdcbdeaec615d9596becd14b7bb87fd38df763de3</originalsourceid><addsrcrecordid>eNpdkctrXCEUxqW0NCHNvqsidNPNTfQ-fGwKQ-gkgSFdTB9LUe9xYrhXU70O9L-vzSQhrRvlnN_3cY4fQu8pOaO0Fec7CHEGfUYI70lD2St03FImG9EK_vrF-wid5nxH6hG11Iu36KjlPZOSdceorMs0NZcPVngLvwoECzg6rPENlBR92Ovs94B_Ql7wjZ8A__CpZLzxAfQOcIu3S9I-YJfiXFVrvegJX8WUAV8HB3bxMeDa38ay3OKVS97qd-iN01OG08f7BH1ff_l2cdVsvl5eX6w2je0lWRraUm6oIYYw7owRRBqrCQgzWjOCBsvoMMpBMgN2pL3hleFu7MToOOtG6E7Q54PvfTEzjBZCnXVS98nPOv1WUXv1byf4W7WLe9VLxnrGq8GnR4MU69_kRc0-W5gmHSCWrKggXMiWDrKiH_9D72JJoa6nqBy6TtCWD5UiB8qmmHMC9zwMJepvrOoQ60o9xKooq5IPL5d4FjyF2P0BJFGhSg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1953381275</pqid></control><display><type>article</type><title>Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa</title><source>American Society for Microbiology Journals</source><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Mentoor, Juliet L D ; Lubisi, Alison B ; Gerdes, Truuska ; Human, Stacey ; Williams, June H ; Venter, Marietjie</creator><creatorcontrib>Mentoor, Juliet L D ; Lubisi, Alison B ; Gerdes, Truuska ; Human, Stacey ; Williams, June H ; Venter, Marietjie</creatorcontrib><description>We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however, there are a lack of sequencing data from recent fatal cases in Southern Africa, where these strains likely originate. A better understanding of the genetic composition of highly neuroinvasive lineage 2 strains may facilitate the identification of putative genetic factors associated with increased virulence.</description><identifier>ISSN: 2169-8287</identifier><identifier>EISSN: 2169-8287</identifier><identifier>EISSN: 2576-098X</identifier><identifier>DOI: 10.1128/genomea.00740-16</identifier><identifier>PMID: 27469963</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Viruses ; West Nile virus</subject><ispartof>Genome announcements (Washington, DC), 2016-07, Vol.4 (4)</ispartof><rights>Copyright © 2016 Mentoor et al.</rights><rights>Copyright © 2016 Mentoor et al. This work is licensed under the Creative Commons Attribution License (https://creativecommons.org/licenses/by/3.0/) (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2016 Mentoor et al. 2016 Mentoor et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-1217b1b0b067fbb809bca0e8bdcbdeaec615d9596becd14b7bb87fd38df763de3</citedby><cites>FETCH-LOGICAL-c490t-1217b1b0b067fbb809bca0e8bdcbdeaec615d9596becd14b7bb87fd38df763de3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966467/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966467/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27469963$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mentoor, Juliet L D</creatorcontrib><creatorcontrib>Lubisi, Alison B</creatorcontrib><creatorcontrib>Gerdes, Truuska</creatorcontrib><creatorcontrib>Human, Stacey</creatorcontrib><creatorcontrib>Williams, June H</creatorcontrib><creatorcontrib>Venter, Marietjie</creatorcontrib><title>Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa</title><title>Genome announcements (Washington, DC)</title><addtitle>Genome Announc</addtitle><description>We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however, there are a lack of sequencing data from recent fatal cases in Southern Africa, where these strains likely originate. A better understanding of the genetic composition of highly neuroinvasive lineage 2 strains may facilitate the identification of putative genetic factors associated with increased virulence.</description><subject>Viruses</subject><subject>West Nile virus</subject><issn>2169-8287</issn><issn>2169-8287</issn><issn>2576-098X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkctrXCEUxqW0NCHNvqsidNPNTfQ-fGwKQ-gkgSFdTB9LUe9xYrhXU70O9L-vzSQhrRvlnN_3cY4fQu8pOaO0Fec7CHEGfUYI70lD2St03FImG9EK_vrF-wid5nxH6hG11Iu36KjlPZOSdceorMs0NZcPVngLvwoECzg6rPENlBR92Ovs94B_Ql7wjZ8A__CpZLzxAfQOcIu3S9I-YJfiXFVrvegJX8WUAV8HB3bxMeDa38ay3OKVS97qd-iN01OG08f7BH1ff_l2cdVsvl5eX6w2je0lWRraUm6oIYYw7owRRBqrCQgzWjOCBsvoMMpBMgN2pL3hleFu7MToOOtG6E7Q54PvfTEzjBZCnXVS98nPOv1WUXv1byf4W7WLe9VLxnrGq8GnR4MU69_kRc0-W5gmHSCWrKggXMiWDrKiH_9D72JJoa6nqBy6TtCWD5UiB8qmmHMC9zwMJepvrOoQ60o9xKooq5IPL5d4FjyF2P0BJFGhSg</recordid><startdate>20160728</startdate><enddate>20160728</enddate><creator>Mentoor, Juliet L D</creator><creator>Lubisi, Alison B</creator><creator>Gerdes, Truuska</creator><creator>Human, Stacey</creator><creator>Williams, June H</creator><creator>Venter, Marietjie</creator><general>American Society for Microbiology</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160728</creationdate><title>Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa</title><author>Mentoor, Juliet L D ; Lubisi, Alison B ; Gerdes, Truuska ; Human, Stacey ; Williams, June H ; Venter, Marietjie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c490t-1217b1b0b067fbb809bca0e8bdcbdeaec615d9596becd14b7bb87fd38df763de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Viruses</topic><topic>West Nile virus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mentoor, Juliet L D</creatorcontrib><creatorcontrib>Lubisi, Alison B</creatorcontrib><creatorcontrib>Gerdes, Truuska</creatorcontrib><creatorcontrib>Human, Stacey</creatorcontrib><creatorcontrib>Williams, June H</creatorcontrib><creatorcontrib>Venter, Marietjie</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Genome announcements (Washington, DC)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mentoor, Juliet L D</au><au>Lubisi, Alison B</au><au>Gerdes, Truuska</au><au>Human, Stacey</au><au>Williams, June H</au><au>Venter, Marietjie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa</atitle><jtitle>Genome announcements (Washington, DC)</jtitle><addtitle>Genome Announc</addtitle><date>2016-07-28</date><risdate>2016</risdate><volume>4</volume><issue>4</issue><issn>2169-8287</issn><eissn>2169-8287</eissn><eissn>2576-098X</eissn><abstract>We report here the complete genome sequence of a lineage 2 West Nile virus (WNV) strain that resulted in fatal neurological disease in a horse in South Africa. Several recent reports exist of neurological disease associated with lineage 2 WNV in humans and horses in South Africa and Europe; however, there are a lack of sequencing data from recent fatal cases in Southern Africa, where these strains likely originate. A better understanding of the genetic composition of highly neuroinvasive lineage 2 strains may facilitate the identification of putative genetic factors associated with increased virulence.</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>27469963</pmid><doi>10.1128/genomea.00740-16</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2169-8287
ispartof Genome announcements (Washington, DC), 2016-07, Vol.4 (4)
issn 2169-8287
2169-8287
2576-098X
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4966467
source American Society for Microbiology Journals; PubMed Central Open Access; PubMed Central
subjects Viruses
West Nile virus
title Full-Genome Sequence of a Neuroinvasive West Nile Virus Lineage 2 Strain from a Fatal Horse Infection in South Africa
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T04%3A36%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Full-Genome%20Sequence%20of%20a%20Neuroinvasive%20West%20Nile%20Virus%20Lineage%202%20Strain%20from%20a%20Fatal%20Horse%20Infection%20in%20South%20Africa&rft.jtitle=Genome%20announcements%20(Washington,%20DC)&rft.au=Mentoor,%20Juliet%20L%20D&rft.date=2016-07-28&rft.volume=4&rft.issue=4&rft.issn=2169-8287&rft.eissn=2169-8287&rft_id=info:doi/10.1128/genomea.00740-16&rft_dat=%3Cproquest_pubme%3E1807892159%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1953381275&rft_id=info:pmid/27469963&rfr_iscdi=true