Integrative epigenomic analysis reveals unique epigenetic signatures involved in unipotency of mouse female germline stem cells

Germline stem cells play an essential role in establishing the fertility of an organism. Although extensively characterized, the regulatory mechanisms that govern the fundamental properties of mammalian female germline stem cells remain poorly understood. We generate genome-wide profiles of the hist...

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Veröffentlicht in:	Genome Biology 2016-07, Vol.17 (1), p.162-162, Article 162
Hauptverfasser:	Zhang, Xiao-Li, Wu, Jun, Wang, Jian, Shen, Tingting, Li, Hua, Lu, Jun, Gu, Yunzhao, Kang, Yani, Wong, Chee-Hong, Ngan, Chew Yee, Shao, Zhifeng, Wu, Ji, Zhao, Xiaodong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Germline Stem Cells - metabolism Animals BASIC BIOLOGICAL SCIENCES Biotechnology & Applied Microbiology Cell Lineage - genetics ChIP-Seq Chromatin - genetics Chromatin - metabolism Deoxyribonucleic acid DNA DNA methylation DNA Methylation - genetics DNA-directed RNA polymerase Embryo cells Embryonic stem cells Enhancers Epigenetic inheritance Epigenetics Epigenome Epigenomics Female Female germline stem cell females Fertility Fertility - genetics Gene expression Genetic aspects Genetics & Heredity Genome Genomes Genomics germ cells histones Histones - genetics Histones - metabolism Male males Mice Mouse Embryonic Stem Cells Oogonial Stem Cells - metabolism Physiological aspects RNA polymerase Stem cell transplantation Stem cells Transcription transcription factors Transcriptome - genetics transcriptomics
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