ATR-mediated regulation of nuclear and cellular plasticity

ATR (Ataxia Telangiectasia and Rad3-related) is a member of the Phosphatidylinositol 3-kinase-related kinases (PIKKs) family, amongst six other vertebrate proteins known so far. ATR is indispensable for cell survival and its essential role is in sensing DNA damage and initiating appropriate repair r...

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Veröffentlicht in:	DNA repair 2016-08, Vol.44, p.143-150
Hauptverfasser:	Kidiyoor, Gururaj Rao, Kumar, Amit, Foiani, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Ataxia Telangiectasia Mutated Proteins - genetics Ataxia Telangiectasia Mutated Proteins - metabolism ATR Cell Nucleolus - metabolism Cell Nucleolus - ultrastructure Cell Plasticity Cellular plasticity Centrosome Centrosome - metabolism Centrosome - ultrastructure DNA - chemistry DNA - metabolism DNA Damage DNA Repair Eukaryotic Cells - metabolism Eukaryotic Cells - ultrastructure Humans Nuclear envelope Nuclear Envelope - metabolism Nuclear Envelope - ultrastructure Nucleolus PIKK
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