Helicobacter saguini, a Novel Helicobacter Isolated from Cotton-Top Tamarins with Ulcerative Colitis, Has Proinflammatory Properties and Induces Typhlocolitis and Dysplasia in Gnotobiotic IL-10-/- Mice

A urease-negative, fusiform, novel bacterium named Helicobacter saguini was isolated from the intestines and feces of cotton-top tamarins (CTTs) with chronic colitis. Helicobacter sp. was detected in 69% of feces or intestinal samples from 116 CTTs. The draft genome sequence, obtained by Illumina Mi...

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Veröffentlicht in:	Infection and immunity 2016-08, Vol.84 (8), p.2307-2316
Hauptverfasser:	Shen, Z, Mannion, A, Whary, M T, Muthupalani, S, Sheh, A, Feng, Y, Gong, G, Vandamme, P, Holcombe, H R, Paster, B J, Fox, J G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Bacterial - immunology Cell Line Colitis - genetics Colitis - immunology Colitis - microbiology Colitis - pathology Colitis, Ulcerative - veterinary Cytokines - genetics Disease Models, Animal Feces - microbiology Gene Expression Genome, Bacterial Helicobacter Helicobacter - classification Helicobacter - isolation & purification Helicobacter - physiology Helicobacter pylori Histones - metabolism Host Response and Inflammation Humans Inflammation Mediators - metabolism Interleukin-10 - deficiency Mice Mice, Knockout Monkey Diseases - microbiology Phylogeny RNA, Ribosomal, 16S - genetics
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