Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease

Chronic obstructive pulmonary disease (COPD) susceptibility is in part related to genetic variants. Most genetic studies have been focused on genome-wide common variants without a specific focus on coding variants, but common and rare coding variants may also affect COPD susceptibility. To identify...

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Veröffentlicht in:	American journal of respiratory and critical care medicine 2016-07, Vol.194 (1), p.48-57
Hauptverfasser:	Hobbs, Brian D, Parker, Margaret M, Chen, Han, Lao, Taotao, Hardin, Megan, Qiao, Dandi, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Yim, Jae-Joon, Kim, Woo Jin, Kim, Deog Kyeom, Castaldi, Peter J, Hersh, Craig P, Morrow, Jarrett, Celli, Bartolome R, Pinto-Plata, Victor M, Criner, Gerald J, Marchetti, Nathaniel, Bueno, Raphael, Agustí, Alvar, Make, Barry J, Crapo, James D, Calverley, Peter M, Donner, Claudio F, Lomas, David A, Wouters, Emiel F M, Vestbo, Jorgen, Paré, Peter D, Levy, Robert D, Rennard, Stephen I, Zhou, Xiaobo, Laird, Nan M, Lin, Xihong, Beaty, Terri H, Silverman, Edwin K, Cho, Michael H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Exome - genetics Female Gene Frequency - genetics Genetic Predisposition to Disease - genetics Humans Interleukin-27 - genetics Male Middle Aged Original Pulmonary Disease, Chronic Obstructive - genetics
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