Correlation of EGFR-expression with safety and efficacy outcomes in SQUIRE: a randomized, multicenter, open-label, phase III study of gemcitabine–cisplatin plus necitumumab versus gemcitabine–cisplatin alone in the first-line treatment of patients with stage IV squamous non-small-cell lung cancer

SQUIRE demonstrated addition of necitumumab to gemcitabine and cisplatin significantly improved survival in patients with stage IV sq-NSCLC. Here, we report additional outcomes for the subpopulation of patients with tumor epidermal growth factor receptor (EGFR) protein expression. Patients with path...

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Veröffentlicht in:Annals of oncology 2016-08, Vol.27 (8), p.1573-1579
Hauptverfasser: Paz-Ares, L., Socinski, M.A., Shahidi, J., Hozak, R.R., Soldatenkova, V., Kurek, R., Varella-Garcia, M., Thatcher, N., Hirsch, F.R.
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