Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians
In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels...
Gespeichert in:
| Veröffentlicht in: | Journal of occupational medicine and toxicology (London, England) England), 2016-07, Vol.11 (1), p.36-36, Article 36 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 36 |
|---|---|
| container_issue | 1 |
| container_start_page | 36 |
| container_title | Journal of occupational medicine and toxicology (London, England) |
| container_volume | 11 |
| creator | Grešner, Peter Świercz, Radosław Król, Magdalena Beata Twardowska, Ewa Gromadzińska, Jolanta Wąsowicz, Wojciech |
| description | In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels of selected VOCs in nail salons were also analyzed and tested for associations with seasonal variations of the levels of biomarkers among nail technicians.
The study enrolled 145 female nail technicians and 145 healthy unexposed female controls. The airborne VOCs and levels of biomarkers were assessed by GC-MS chromatography and absorption/fluorescence spectrophotometry, respectively.
Plasma levels of thiobarbituric acid reactive species, ceruloplasmin, the activity of glutathione peroxidase (GPx1) and the SOD1/GPx1 activity ratio presented significant differences between the so-called "hot" and "cold" seasons in the case of nail technicians as well as in unexposed controls (p |
| doi_str_mv | 10.1186/s12995-016-0125-6 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4957283</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A469268759</galeid><sourcerecordid>A469268759</sourcerecordid><originalsourceid>FETCH-LOGICAL-c494t-2860a93c386256bf435cbc78288affbc1ac26ad87aa990f381111b7551eea5843</originalsourceid><addsrcrecordid>eNptUsFu1DAQjRCIlsIHcEGWuHBJiZPYsS-gVaEFaSUucLYmzmTXxYkXO9m2H8b_Mbtbqi3ClmVr5r1nz_hl2WtenHOu5PvES61FXnBJqxS5fJKd8qamg2yqp0fnk-xFStdFUQtRVM-zk5ISVcP1afb7U8DEpjWyZbjJPW7Rs2DtvIHJhRE8w9tNSHNENgW2DZ7CHlmIKxidZTYMmzCPXWLgJ4x7nYSQ9swtRLdXYaGnqEc7YccGiD8xpl0s3LqOAFviTBFT-sgWzELC3IZxisFTeO7umBvZCM6zCe2aLnUwppfZsx58wlf3-1n24_Lz94sv-fLb1deLxTK3ta6nvFSyAF3ZSslSyLavK2Fb26hSKej71nKwpYRONQBaF32lOI22EYIjglB1dZZ9OOhu5nbAziK9C7zZREdl3JkAzjzOjG5tVmFrai2aUlUk8O5eIIZfM6bJDC5Z9B5GDHMyXBVNoUouBUHf_gO9DnOkRh5QWiiljlAr8Gjc2Ae61-5EzaKWupSqEZpQ5_9B0exwcNRd7OkXHxP4gWBjSCli_1AjL8zOa-bgNUNeMzuvGUmcN8fNeWD8NVf1Bzbd0yo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1807958885</pqid></control><display><type>article</type><title>Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians</title><source>DOAJ Directory of Open Access Journals</source><source>SpringerLink Journals</source><source>PubMed Central Open Access</source><source>Springer Nature OA Free Journals</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Grešner, Peter ; Świercz, Radosław ; Król, Magdalena Beata ; Twardowska, Ewa ; Gromadzińska, Jolanta ; Wąsowicz, Wojciech</creator><creatorcontrib>Grešner, Peter ; Świercz, Radosław ; Król, Magdalena Beata ; Twardowska, Ewa ; Gromadzińska, Jolanta ; Wąsowicz, Wojciech</creatorcontrib><description>In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels of selected VOCs in nail salons were also analyzed and tested for associations with seasonal variations of the levels of biomarkers among nail technicians.
The study enrolled 145 female nail technicians and 145 healthy unexposed female controls. The airborne VOCs and levels of biomarkers were assessed by GC-MS chromatography and absorption/fluorescence spectrophotometry, respectively.
Plasma levels of thiobarbituric acid reactive species, ceruloplasmin, the activity of glutathione peroxidase (GPx1) and the SOD1/GPx1 activity ratio presented significant differences between the so-called "hot" and "cold" seasons in the case of nail technicians as well as in unexposed controls (p < <0.0001 for all four biomarkers). The pattern of these variations among nail technicians was found to be significantly different compared to that of the control subjects (p < <0.0001). Although such differences might intuitively be attributed to occupational exposure of nail technicians to VOCs, which was found to be higher during the "cold" season compared to the "hot" one, our study provided only limited evidence in favor of the hypothesis, that the different pattern of seasonal variations of biomarkers among nail technicians might have resulted from seasonal fluctuations in their occupational exposure to VOCs.
Further investigation is thus needed in order to elucidate the effect of low-level occupational exposure to VOCs on seasonal variations of biomarkers of oxidative stress.</description><identifier>ISSN: 1745-6673</identifier><identifier>EISSN: 1745-6673</identifier><identifier>DOI: 10.1186/s12995-016-0125-6</identifier><identifier>PMID: 27453719</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Health aspects ; Occupational health ; Occupational health and safety ; Oxidative stress ; Risk factors ; Seasonal variations (Diseases) ; Volatile organic compounds</subject><ispartof>Journal of occupational medicine and toxicology (London, England), 2016-07, Vol.11 (1), p.36-36, Article 36</ispartof><rights>COPYRIGHT 2016 BioMed Central Ltd.</rights><rights>Copyright BioMed Central 2016</rights><rights>The Author(s). 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-2860a93c386256bf435cbc78288affbc1ac26ad87aa990f381111b7551eea5843</citedby><cites>FETCH-LOGICAL-c494t-2860a93c386256bf435cbc78288affbc1ac26ad87aa990f381111b7551eea5843</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957283/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957283/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27453719$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Grešner, Peter</creatorcontrib><creatorcontrib>Świercz, Radosław</creatorcontrib><creatorcontrib>Król, Magdalena Beata</creatorcontrib><creatorcontrib>Twardowska, Ewa</creatorcontrib><creatorcontrib>Gromadzińska, Jolanta</creatorcontrib><creatorcontrib>Wąsowicz, Wojciech</creatorcontrib><title>Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians</title><title>Journal of occupational medicine and toxicology (London, England)</title><addtitle>J Occup Med Toxicol</addtitle><description>In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels of selected VOCs in nail salons were also analyzed and tested for associations with seasonal variations of the levels of biomarkers among nail technicians.
The study enrolled 145 female nail technicians and 145 healthy unexposed female controls. The airborne VOCs and levels of biomarkers were assessed by GC-MS chromatography and absorption/fluorescence spectrophotometry, respectively.
Plasma levels of thiobarbituric acid reactive species, ceruloplasmin, the activity of glutathione peroxidase (GPx1) and the SOD1/GPx1 activity ratio presented significant differences between the so-called "hot" and "cold" seasons in the case of nail technicians as well as in unexposed controls (p < <0.0001 for all four biomarkers). The pattern of these variations among nail technicians was found to be significantly different compared to that of the control subjects (p < <0.0001). Although such differences might intuitively be attributed to occupational exposure of nail technicians to VOCs, which was found to be higher during the "cold" season compared to the "hot" one, our study provided only limited evidence in favor of the hypothesis, that the different pattern of seasonal variations of biomarkers among nail technicians might have resulted from seasonal fluctuations in their occupational exposure to VOCs.
Further investigation is thus needed in order to elucidate the effect of low-level occupational exposure to VOCs on seasonal variations of biomarkers of oxidative stress.</description><subject>Health aspects</subject><subject>Occupational health</subject><subject>Occupational health and safety</subject><subject>Oxidative stress</subject><subject>Risk factors</subject><subject>Seasonal variations (Diseases)</subject><subject>Volatile organic compounds</subject><issn>1745-6673</issn><issn>1745-6673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptUsFu1DAQjRCIlsIHcEGWuHBJiZPYsS-gVaEFaSUucLYmzmTXxYkXO9m2H8b_Mbtbqi3ClmVr5r1nz_hl2WtenHOu5PvES61FXnBJqxS5fJKd8qamg2yqp0fnk-xFStdFUQtRVM-zk5ISVcP1afb7U8DEpjWyZbjJPW7Rs2DtvIHJhRE8w9tNSHNENgW2DZ7CHlmIKxidZTYMmzCPXWLgJ4x7nYSQ9swtRLdXYaGnqEc7YccGiD8xpl0s3LqOAFviTBFT-sgWzELC3IZxisFTeO7umBvZCM6zCe2aLnUwppfZsx58wlf3-1n24_Lz94sv-fLb1deLxTK3ta6nvFSyAF3ZSslSyLavK2Fb26hSKej71nKwpYRONQBaF32lOI22EYIjglB1dZZ9OOhu5nbAziK9C7zZREdl3JkAzjzOjG5tVmFrai2aUlUk8O5eIIZfM6bJDC5Z9B5GDHMyXBVNoUouBUHf_gO9DnOkRh5QWiiljlAr8Gjc2Ae61-5EzaKWupSqEZpQ5_9B0exwcNRd7OkXHxP4gWBjSCli_1AjL8zOa-bgNUNeMzuvGUmcN8fNeWD8NVf1Bzbd0yo</recordid><startdate>20160721</startdate><enddate>20160721</enddate><creator>Grešner, Peter</creator><creator>Świercz, Radosław</creator><creator>Król, Magdalena Beata</creator><creator>Twardowska, Ewa</creator><creator>Gromadzińska, Jolanta</creator><creator>Wąsowicz, Wojciech</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7T2</scope><scope>7U7</scope><scope>7X7</scope><scope>7XB</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20160721</creationdate><title>Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians</title><author>Grešner, Peter ; Świercz, Radosław ; Król, Magdalena Beata ; Twardowska, Ewa ; Gromadzińska, Jolanta ; Wąsowicz, Wojciech</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-2860a93c386256bf435cbc78288affbc1ac26ad87aa990f381111b7551eea5843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Health aspects</topic><topic>Occupational health</topic><topic>Occupational health and safety</topic><topic>Oxidative stress</topic><topic>Risk factors</topic><topic>Seasonal variations (Diseases)</topic><topic>Volatile organic compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Grešner, Peter</creatorcontrib><creatorcontrib>Świercz, Radosław</creatorcontrib><creatorcontrib>Król, Magdalena Beata</creatorcontrib><creatorcontrib>Twardowska, Ewa</creatorcontrib><creatorcontrib>Gromadzińska, Jolanta</creatorcontrib><creatorcontrib>Wąsowicz, Wojciech</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Toxicology Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of occupational medicine and toxicology (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Grešner, Peter</au><au>Świercz, Radosław</au><au>Król, Magdalena Beata</au><au>Twardowska, Ewa</au><au>Gromadzińska, Jolanta</au><au>Wąsowicz, Wojciech</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians</atitle><jtitle>Journal of occupational medicine and toxicology (London, England)</jtitle><addtitle>J Occup Med Toxicol</addtitle><date>2016-07-21</date><risdate>2016</risdate><volume>11</volume><issue>1</issue><spage>36</spage><epage>36</epage><pages>36-36</pages><artnum>36</artnum><issn>1745-6673</issn><eissn>1745-6673</eissn><abstract>In this study we tested whether the seasonal variations in levels of selected biomarkers of oxidative stress in female nail technicians occupationally exposed to low levels of volatile organic compounds (VOCs) differ significantly from those observed among healthy unexposed controls. Airborne levels of selected VOCs in nail salons were also analyzed and tested for associations with seasonal variations of the levels of biomarkers among nail technicians.
The study enrolled 145 female nail technicians and 145 healthy unexposed female controls. The airborne VOCs and levels of biomarkers were assessed by GC-MS chromatography and absorption/fluorescence spectrophotometry, respectively.
Plasma levels of thiobarbituric acid reactive species, ceruloplasmin, the activity of glutathione peroxidase (GPx1) and the SOD1/GPx1 activity ratio presented significant differences between the so-called "hot" and "cold" seasons in the case of nail technicians as well as in unexposed controls (p < <0.0001 for all four biomarkers). The pattern of these variations among nail technicians was found to be significantly different compared to that of the control subjects (p < <0.0001). Although such differences might intuitively be attributed to occupational exposure of nail technicians to VOCs, which was found to be higher during the "cold" season compared to the "hot" one, our study provided only limited evidence in favor of the hypothesis, that the different pattern of seasonal variations of biomarkers among nail technicians might have resulted from seasonal fluctuations in their occupational exposure to VOCs.
Further investigation is thus needed in order to elucidate the effect of low-level occupational exposure to VOCs on seasonal variations of biomarkers of oxidative stress.</abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>27453719</pmid><doi>10.1186/s12995-016-0125-6</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1745-6673 |
| ispartof | Journal of occupational medicine and toxicology (London, England), 2016-07, Vol.11 (1), p.36-36, Article 36 |
| issn | 1745-6673 1745-6673 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4957283 |
| source | DOAJ Directory of Open Access Journals; SpringerLink Journals; PubMed Central Open Access; Springer Nature OA Free Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Health aspects Occupational health Occupational health and safety Oxidative stress Risk factors Seasonal variations (Diseases) Volatile organic compounds |
| title | Does the Low-level occupational exposure to volatile organic compounds alter the seasonal variation of selected markers of oxidative stress? A case-control study in nail technicians |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T12%3A24%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Does%20the%20Low-level%20occupational%20exposure%20to%20volatile%20organic%20compounds%20alter%20the%20seasonal%20variation%20of%20selected%20markers%20of%20oxidative%20stress?%20A%20case-control%20study%20in%20nail%20technicians&rft.jtitle=Journal%20of%20occupational%20medicine%20and%20toxicology%20(London,%20England)&rft.au=Gre%C5%A1ner,%20Peter&rft.date=2016-07-21&rft.volume=11&rft.issue=1&rft.spage=36&rft.epage=36&rft.pages=36-36&rft.artnum=36&rft.issn=1745-6673&rft.eissn=1745-6673&rft_id=info:doi/10.1186/s12995-016-0125-6&rft_dat=%3Cgale_pubme%3EA469268759%3C/gale_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1807958885&rft_id=info:pmid/27453719&rft_galeid=A469268759&rfr_iscdi=true |