A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol

Vascular dementia is the second most common cause of dementia affecting over seven million people worldwide, yet there are no licensed treatments. There is an urgent need for a clinical trial in this patient group. Subcortical ischaemic vascular dementia is the most common variant of vascular dement...

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Veröffentlicht in:	Current controlled trials in cardiovascular medicine 2016-07, Vol.17 (1), p.324, Article 324
Hauptverfasser:	Greenan, Caroline, Murphy, Lynn, Yu, Ly-Mee, Kehoe, Patrick G, Coulthard, Elizabeth, Bath, Philip, Stewart, Robert, Jones, Rob, Corbett, Anne, Thomas, Alan, Connelly, Peter, Arrojo, Frank, Canning, Rachel, Wallach, Sylvia, Henderson, Catherine, McGuinness, Bernadette, O'Sullivan, Mike, Holmes, Clive, Knapp, Martin, Ballard, Clive, Passmore, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Alzheimer's disease Amlodipine - adverse effects Amlodipine - therapeutic use Brain Ischemia - diagnosis Brain Ischemia - drug therapy Brain Ischemia - physiopathology Brain Ischemia - psychology Calcium Channel Blockers - adverse effects Calcium Channel Blockers - therapeutic use Caregivers Clinical medicine Clinical Protocols Clinical trials Cognition - drug effects Cognitive ability Dementia Dementia, Vascular - diagnosis Dementia, Vascular - drug therapy Dementia, Vascular - physiopathology Dementia, Vascular - psychology Double-Blind Method Female Health services Humans Ischemia Magnetic Resonance Imaging Male Middle Aged Neuropsychological Tests Quality of Life Questionnaires Research Design Study Protocol Time Factors Treatment Outcome United Kingdom
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