Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca2+ oscillations in mouse pancreatic acinar cells

Emerging evidence demonstrates that the blockade of intracellular Ca 2+ signals may protect pancreatic acinar cells against Ca 2+ overload, intracellular protease activation, and necrosis. The activation of cannabinoid receptor subtype 2 (CB 2 R) prevents acinar cell pathogenesis in animal models of...

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Veröffentlicht in:Scientific reports 2016-07, Vol.6 (1), p.29757, Article 29757
Hauptverfasser: Huang, Zebing, Wang, Haiyan, Wang, Jingke, Zhao, Mengqin, Sun, Nana, Sun, Fangfang, Shen, Jianxin, Zhang, Haiying, Xia, Kunkun, Chen, Dejie, Gao, Ming, Hammer, Ronald P., Liu, Qingrong, Xi, Zhengxiong, Fan, Xuegong, Wu, Jie
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Sprache:eng
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