The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873

Emerging evidences suggest that necrosis is programmed and is one of the main forms of cell death in the pathological process in cardiac diseases. Long noncoding RNAs (lncRNAs) are emerging as new players in gene regulation. However, it is not yet clear whether lncRNAs can regulate necrosis in cardi...

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Veröffentlicht in:	Cell death and differentiation 2016-08, Vol.23 (8), p.1394-1405
Hauptverfasser:	Wang, K, Liu, F, Liu, C-Y, An, T, Zhang, J, Zhou, L-Y, Wang, M, Dong, Y-H, Li, N, Gao, J-N, Zhao, Y-F, Li, P-F
Format:	Artikel
Sprache:	eng
Schlagworte:	101/28 13 13/89 3' Untranslated Regions 42/89 631/337 631/80 692/699/75 96 96/1 96/63 96/95 Animals Antagomirs - metabolism Apoptosis Base Sequence Biochemistry Biomedical and Life Sciences Cardiology Cardiomyocytes Cell Biology Cell Cycle Analysis Cell death Cells, Cultured Heart attacks Hydrogen Peroxide - toxicity Ischemia Kinases Life Sciences Male Medicine Mice Mice, Inbred C57BL MicroRNAs MicroRNAs - antagonists & inhibitors MicroRNAs - genetics MicroRNAs - metabolism Myocardial Reperfusion Injury - etiology Myocardial Reperfusion Injury - pathology Myocardial Reperfusion Injury - veterinary Myocytes, Cardiac - cytology Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Original Paper Promoter Regions, Genetic Proteins Receptor-Interacting Protein Serine-Threonine Kinases - antagonists & inhibitors Receptor-Interacting Protein Serine-Threonine Kinases - genetics Receptor-Interacting Protein Serine-Threonine Kinases - metabolism RNA, Long Noncoding - antagonists & inhibitors RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Sequence Alignment Stem Cells Tumor Suppressor Protein p53 - antagonists & inhibitors Tumor Suppressor Protein p53 - genetics Tumor Suppressor Protein p53 - metabolism
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