Identifying Effective Enzyme Activity Targets for Recombinant Class I and Class II Collagenase for Successful Human Islet Isolation

Isolation following a good manufacturing practice-compliant, human islet product requires development of a robust islet isolation procedure where effective limits of key reagents are known. The enzymes used for islet isolation are critical but little is known about the doses of class I and class II...

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Veröffentlicht in:Transplantation direct 2016-01, Vol.2 (1), p.e54-e54
Hauptverfasser: Balamurugan, Appakalai N., Green, Michael L., Breite, Andrew G., Loganathan, Gopalakrishnan, Wilhelm, Joshua J., Tweed, Benjamin, Vargova, Lenka, Lockridge, Amber, Kuriti, Manikya, Hughes, Michael G., Williams, Stuart K., Hering, Bernhard J., Dwulet, Francis E., McCarthy, Robert C.
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Sprache:eng
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