The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA−/VacA− H. pylori

Background Helicobacter pylori ( H. pylori) is a well-recognized gastroduodenal pathogen and class I carcinogen. Dual oxidase-2 (DUOX2), a member of NADPH oxidase family, has several critical physiological functions, including thyroid hormone biosynthesis and host mucosal defense. Aim To investigate...

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Veröffentlicht in:	Digestive diseases and sciences 2016-08, Vol.61 (8), p.2328-2337
Hauptverfasser:	Li, Hongqian, Zhou, Yunfeng, Zheng, Yufeng, Guo, Hong, Gao, Lei, Chen, Pan, Feng, Dandan, Wu, Lijuan, Yang, Moli, Qi, Yanli, Guo, Hao, Chang, Yongchao, Chu, Fong-Fong, Gao, Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Analysis Antibodies, Bacterial - immunology Antigens, Bacterial - immunology Bacterial Proteins - immunology Biochemistry Blotting, Western Dual Oxidases Enzyme-Linked Immunosorbent Assay Female Gastric Mucosa - metabolism Gastritis - genetics Gastritis - immunology Gastritis - metabolism Gastritis - microbiology Gastritis, Atrophic - genetics Gastritis, Atrophic - immunology Gastritis, Atrophic - metabolism Gastritis, Atrophic - microbiology Gastroenterology Gene expression Genes Genetic aspects Genetic research Health aspects Helicobacter infections Helicobacter Infections - genetics Helicobacter Infections - immunology Helicobacter Infections - metabolism Helicobacter Infections - microbiology Helicobacter pylori Helicobacter pylori - immunology Hepatology Humans Immunoglobulin G Immunoglobulin G - immunology Immunohistochemistry Infection Inflammation Lactoperoxidase - genetics Male Medical research Medicine Medicine & Public Health Medicine, Experimental Membrane Glycoproteins - genetics Membrane Glycoproteins - metabolism Middle Aged NADPH Oxidase 1 NADPH Oxidase 2 NADPH Oxidases - genetics NADPH Oxidases - metabolism Oncology Original Original Article Oxidases Peptic Ulcer - genetics Peptic Ulcer - immunology Peptic Ulcer - metabolism Peptic Ulcer - microbiology Peroxidase - metabolism Real-Time Polymerase Chain Reaction RNA RNA, Messenger - metabolism Thyroid gland Transplant Surgery Young Adult
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