Serotonergic dysfunction in the A53T alpha‐synuclein mouse model of Parkinson's disease

Parkinson's disease, neuropathologically defined by the aggregation of α‐synuclein, is characterized by neuropsychiatric symptoms such as depression and anxiety preceding the onset of motor symptoms. A loss of serotonergic neurons or their projections into the hippocampus and alterations in ser...

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Veröffentlicht in:Journal of neurochemistry 2015-11, Vol.135 (3), p.589-597
Hauptverfasser: Deusser, Janina, Schmidt, Stefanie, Ettle, Benjamin, Plötz, Sonja, Huber, Sabine, Müller, Christian P., Masliah, Eliezer, Winkler, Jürgen, Kohl, Zacharias
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Sprache:eng
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