Metabolic pathways promoting cancer cell survival and growth

Burroughs and DeBerardinis discuss the metabolic pathways that tumour cells employ to promote their survival and proliferation, and present the current approaches to study cancer metabolism in an in vivo setting. Activation of oncogenes and loss of tumour suppressors promote metabolic reprogramming...

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Veröffentlicht in:	Nature cell biology 2015-04, Vol.17 (4), p.351-359
Hauptverfasser:	Boroughs, Lindsey K., DeBerardinis, Ralph J.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67 631/67/2327 Animals Cancer Research Carcinogenesis Cell Biology Cell metabolism Cell Proliferation Cell Survival Developmental Biology Energy Metabolism - physiology Genetic aspects Glucose - metabolism Humans Life Sciences Lipid Metabolism - physiology Metabolic Networks and Pathways - physiology Mice Neoplasms - metabolism Nutrient uptake Oncogenes Properties review-article Stem Cells
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