Assessment of free fatty acids and cholesteryl esters delivered in liposomes as novel class of antibiotic

Healthcare associated infections (HAI) with multidrug-resistant (MDR) bacteria continue to be a global threat, highlighting an urgent need for novel antibiotics. In this study, we assessed the potential of free fatty acids and cholesteryl esters that form part of the innate host defense as novel ant...

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Veröffentlicht in:	BMC research notes 2016-07, Vol.9 (1), p.337-337, Article 337
Hauptverfasser:	Cheung Lam, Annie H, Sandoval, Natalie, Wadhwa, Ritambhara, Gilkes, Janine, Do, Thai Q, Ernst, William, Chiang, Su-Ming, Kosina, Suzanne, Howard Xu, H, Fujii, Gary, Porter, Edith
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - pharmacology Antibacterial agents Care and treatment Cholesterol Esters - pharmacology Cross Infection - drug therapy DNA, Bacterial - analysis DNA, Bacterial - genetics Drug Combinations Drug Compounding Drug Resistance, Multiple, Bacterial Drug Synergism Enterococcus faecalis - drug effects Enterococcus faecalis - genetics Enterococcus faecalis - growth & development Erythrocytes - drug effects Esters Fatty acids Fatty Acids, Nonesterified - pharmacology Fluorescent Dyes Health aspects Hemolysis - drug effects Hep G2 Cells Humans Liposomes - chemistry Microbial drug resistance Microbial Sensitivity Tests Organic Chemicals Properties Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - growth & development Sheep Staphylococcus epidermidis - drug effects Staphylococcus epidermidis - genetics Staphylococcus epidermidis - growth & development Vancomycin - pharmacology
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