Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts

RNA polymerase III (RNAPIII) synthesizes a range of highly abundant small stable RNAs, principally pre-tRNAs. Here we report the genome-wide analysis of nascent transcripts attached to RNAPIII under permissive and restrictive growth conditions. This revealed strikingly uneven polymerase distribution...

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Veröffentlicht in:	Genome research 2016-07, Vol.26 (7), p.933-944
Hauptverfasser:	Turowski, Tomasz W, Leśniewska, Ewa, Delan-Forino, Clementine, Sayou, Camille, Boguta, Magdalena, Tollervey, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Gene Expression Regulation, Fungal Genome, Fungal Life Sciences RNA Polymerase III - physiology RNA, Transfer - genetics RNA, Transfer - metabolism Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae Proteins - physiology Sequence Analysis, RNA Terminator Regions, Genetic Transcription, Genetic
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