Validity of acute and chronic tactile sensory testing after spinal cord injury in rats

Spinal cord injury (SCI) impairs sensory systems causing allodynia. Measuring the development of allodynia in rodent models of SCI is challenging due to spinal shock and marked motor impairments. Assessment of SCI-induced allodynia is not standardized across labs, making interpretation of results di...

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Veröffentlicht in:	Experimental neurology 2010-10, Vol.225 (2), p.366-376
Hauptverfasser:	Detloff, Megan Ryan, Clark, Leslie M., Hutchinson, Karen J., Kloos, Anne D., Fisher, Lesley C., Basso, D. Michele
Format:	Artikel
Sprache:	eng
Schlagworte:	Allodynia Analysis of Variance Animals Biological and medical sciences Distraction Female Hyperalgesia - physiopathology Injuries of the nervous system and the skull. Diseases due to physical agents Laminectomy Male Medical sciences Neurology Pain - physiopathology Pain Measurement - methods Random Allocation Rats Rats, Sprague-Dawley Sensitivity and Specificity Sensory Thresholds - physiology Spinal Cord Injuries - physiopathology Thoracic Vertebrae Touch - physiology Traumas. Diseases due to physical agents von Frey Hair Withdrawal threshold
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