Calnexin, an ER-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer

Background Colorectal cancer (CRC) is a leading cause of cancer mortality in the Western world and commonly treated with genotoxic chemotherapy. Stress in the endoplasmic reticulum (ER) was implicated to contribute to chemotherapeutic resistance. Hence, ER stress related protein may be of prognostic...

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Veröffentlicht in:	Journal of translational medicine 2016-07, Vol.14 (1), Article 196
Hauptverfasser:	Ryan, Deborah, Carberry, Steven, Murphy, Ãine C, Lindner, Andreas U, Fay, Joanna, Hector, Suzanne, McCawley, Niamh, Bacon, Orna, Concannon, Caoimhin G, Kay, Elaine W, McNamara, Deborah A, Prehn, Jochen H. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Care and treatment Chemotherapy Colorectal cancer Diagnosis Endoplasmic reticulum Health aspects Heat shock proteins Tumor proteins
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