Enterovirus and parechovirus infection in children: a brief overview
Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of...
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| Veröffentlicht in: | European journal of pediatrics 2016-08, Vol.175 (8), p.1023-1029 |
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| container_title | European journal of pediatrics |
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| creator | de Crom, S. C. M. Rossen, J. W. A. van Furth, A. M. Obihara, C. C. |
| description | Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children.
Conclusions
: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.
What is known:
•
EV and HPeV are a frequent cause of infection in children
.
What is new:
•
This review gives a brief overview over EV and HPeV infection in children
. |
| doi_str_mv | 10.1007/s00431-016-2725-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4930465</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1808732903</sourcerecordid><originalsourceid>FETCH-LOGICAL-c503t-8053e98dac3ef35c41445f5ee266df3100212d3ee6dbe05044020c5f5ee981c33</originalsourceid><addsrcrecordid>eNqNkU9v1DAQxS0EotvCB-CCInHhEpjxvyQckKq2QKVKvcDZ8jqTrqusvdjJIr493u5SFaRKPdny_N4bzzzG3iB8QIDmYwaQAmtAXfOGq7p5xhYoBa8RGv2cLUBIqDV23RE7zvkWiqbD9iU74g0qjaAX7PwiTJTi1qc5Vzb01cYmcqvDgw8DucnHUG6VW_mxTxQ-VbZaJk9DFbeUtp5-vWIvBjtmen04T9iPLxffz77VV9dfL89Or2qnQEx1C0pQ1_bWCRqEchKlVIMi4lr3gygjceS9INL9kkCBlMDB3RFdi06IE_Z577uZl2vqHYUp2dFskl_b9NtE682_leBX5iZujewESK2KwfuDQYo_Z8qTWfvsaBxtoDhngy20jeAdiKegKLkQd-i7_9DbOKdQNrGjoMOydVko3FMuxZwTDff_RjC7OM0-TlPiNLs4TVM0bx8OfK_4m18B-B7IpRRuKD1o_ajrHzJ5qg8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1800917914</pqid></control><display><type>article</type><title>Enterovirus and parechovirus infection in children: a brief overview</title><source>MEDLINE</source><source>Springer Nature - Complete Springer Journals</source><creator>de Crom, S. C. M. ; Rossen, J. W. A. ; van Furth, A. M. ; Obihara, C. C.</creator><creatorcontrib>de Crom, S. C. M. ; Rossen, J. W. A. ; van Furth, A. M. ; Obihara, C. C.</creatorcontrib><description>Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children.
Conclusions
: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.
What is known:
•
EV and HPeV are a frequent cause of infection in children
.
What is new:
•
This review gives a brief overview over EV and HPeV infection in children
.</description><identifier>ISSN: 0340-6199</identifier><identifier>EISSN: 1432-1076</identifier><identifier>DOI: 10.1007/s00431-016-2725-7</identifier><identifier>PMID: 27156106</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Child ; Enterovirus ; Enterovirus - isolation & purification ; Enterovirus - pathogenicity ; Enterovirus Infections - diagnosis ; Enterovirus Infections - epidemiology ; Enterovirus Infections - therapy ; Humans ; Medicine ; Medicine & Public Health ; Parechovirus - isolation & purification ; Parechovirus - pathogenicity ; Pediatrics ; Picornaviridae Infections - diagnosis ; Picornaviridae Infections - epidemiology ; Picornaviridae Infections - therapy ; Prevalence ; Prognosis ; Reverse Transcriptase Polymerase Chain Reaction ; Review</subject><ispartof>European journal of pediatrics, 2016-08, Vol.175 (8), p.1023-1029</ispartof><rights>The Author(s) 2016</rights><rights>Springer-Verlag Berlin Heidelberg 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-8053e98dac3ef35c41445f5ee266df3100212d3ee6dbe05044020c5f5ee981c33</citedby><cites>FETCH-LOGICAL-c503t-8053e98dac3ef35c41445f5ee266df3100212d3ee6dbe05044020c5f5ee981c33</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00431-016-2725-7$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00431-016-2725-7$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>230,313,314,776,780,788,881,27899,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27156106$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Crom, S. C. M.</creatorcontrib><creatorcontrib>Rossen, J. W. A.</creatorcontrib><creatorcontrib>van Furth, A. M.</creatorcontrib><creatorcontrib>Obihara, C. C.</creatorcontrib><title>Enterovirus and parechovirus infection in children: a brief overview</title><title>European journal of pediatrics</title><addtitle>Eur J Pediatr</addtitle><addtitle>Eur J Pediatr</addtitle><description>Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children.
Conclusions
: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.
What is known:
•
EV and HPeV are a frequent cause of infection in children
.
What is new:
•
This review gives a brief overview over EV and HPeV infection in children
.</description><subject>Child</subject><subject>Enterovirus</subject><subject>Enterovirus - isolation & purification</subject><subject>Enterovirus - pathogenicity</subject><subject>Enterovirus Infections - diagnosis</subject><subject>Enterovirus Infections - epidemiology</subject><subject>Enterovirus Infections - therapy</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Parechovirus - isolation & purification</subject><subject>Parechovirus - pathogenicity</subject><subject>Pediatrics</subject><subject>Picornaviridae Infections - diagnosis</subject><subject>Picornaviridae Infections - epidemiology</subject><subject>Picornaviridae Infections - therapy</subject><subject>Prevalence</subject><subject>Prognosis</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>Review</subject><issn>0340-6199</issn><issn>1432-1076</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqNkU9v1DAQxS0EotvCB-CCInHhEpjxvyQckKq2QKVKvcDZ8jqTrqusvdjJIr493u5SFaRKPdny_N4bzzzG3iB8QIDmYwaQAmtAXfOGq7p5xhYoBa8RGv2cLUBIqDV23RE7zvkWiqbD9iU74g0qjaAX7PwiTJTi1qc5Vzb01cYmcqvDgw8DucnHUG6VW_mxTxQ-VbZaJk9DFbeUtp5-vWIvBjtmen04T9iPLxffz77VV9dfL89Or2qnQEx1C0pQ1_bWCRqEchKlVIMi4lr3gygjceS9INL9kkCBlMDB3RFdi06IE_Z577uZl2vqHYUp2dFskl_b9NtE682_leBX5iZujewESK2KwfuDQYo_Z8qTWfvsaBxtoDhngy20jeAdiKegKLkQd-i7_9DbOKdQNrGjoMOydVko3FMuxZwTDff_RjC7OM0-TlPiNLs4TVM0bx8OfK_4m18B-B7IpRRuKD1o_ajrHzJ5qg8</recordid><startdate>20160801</startdate><enddate>20160801</enddate><creator>de Crom, S. C. M.</creator><creator>Rossen, J. W. A.</creator><creator>van Furth, A. M.</creator><creator>Obihara, C. 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C. M. ; Rossen, J. W. A. ; van Furth, A. M. ; Obihara, C. C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-8053e98dac3ef35c41445f5ee266df3100212d3ee6dbe05044020c5f5ee981c33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Child</topic><topic>Enterovirus</topic><topic>Enterovirus - isolation & purification</topic><topic>Enterovirus - pathogenicity</topic><topic>Enterovirus Infections - diagnosis</topic><topic>Enterovirus Infections - epidemiology</topic><topic>Enterovirus Infections - therapy</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Parechovirus - isolation & purification</topic><topic>Parechovirus - pathogenicity</topic><topic>Pediatrics</topic><topic>Picornaviridae Infections - diagnosis</topic><topic>Picornaviridae Infections - epidemiology</topic><topic>Picornaviridae Infections - therapy</topic><topic>Prevalence</topic><topic>Prognosis</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>Review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Crom, S. C. M.</creatorcontrib><creatorcontrib>Rossen, J. W. A.</creatorcontrib><creatorcontrib>van Furth, A. M.</creatorcontrib><creatorcontrib>Obihara, C. 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C. M.</au><au>Rossen, J. W. A.</au><au>van Furth, A. M.</au><au>Obihara, C. C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Enterovirus and parechovirus infection in children: a brief overview</atitle><jtitle>European journal of pediatrics</jtitle><stitle>Eur J Pediatr</stitle><addtitle>Eur J Pediatr</addtitle><date>2016-08-01</date><risdate>2016</risdate><volume>175</volume><issue>8</issue><spage>1023</spage><epage>1029</epage><pages>1023-1029</pages><issn>0340-6199</issn><eissn>1432-1076</eissn><abstract>Enterovirus and parechovirus are a frequent cause of infection in children. This review is an overview of what is known from enterovirus and parechovirus infection in children and contains information about the epidemiology, pathogenesis, clinical presentation, diagnosis, treatment, and prognosis of enterovirus and parechovirus infection in children.
Conclusions
: EV and HPeV infections are a frequent cause of infection in childhood. The clinical presentation is diverse. RT-qPCR is the best way to detect an EV or HPeV. Cerebrospinal fluid, blood and feces have the highest sensitivity for detecting an EV or HPeV. There is no treatment for EV and HPeV infections. Two vaccines against EV 71 are just licensed in China and will be available on the private market. Little is known about the prognosis of EV and HPeV infections.
What is known:
•
EV and HPeV are a frequent cause of infection in children
.
What is new:
•
This review gives a brief overview over EV and HPeV infection in children
.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>27156106</pmid><doi>10.1007/s00431-016-2725-7</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | European journal of pediatrics, 2016-08, Vol.175 (8), p.1023-1029 |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Child Enterovirus Enterovirus - isolation & purification Enterovirus - pathogenicity Enterovirus Infections - diagnosis Enterovirus Infections - epidemiology Enterovirus Infections - therapy Humans Medicine Medicine & Public Health Parechovirus - isolation & purification Parechovirus - pathogenicity Pediatrics Picornaviridae Infections - diagnosis Picornaviridae Infections - epidemiology Picornaviridae Infections - therapy Prevalence Prognosis Reverse Transcriptase Polymerase Chain Reaction Review |
| title | Enterovirus and parechovirus infection in children: a brief overview |
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