Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry
The levels of lead in plasma were determined in 16 cases of amyotrophic lateral sclerosis (ALS) and 18 control subjects, using flameless atomic absorption spectrophotometry. The mean values were 0.52+/-0.22 microgram/100ml (ALS) and 0.37+/-0.13 microgram/100ml (controls), the difference is statistic...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1978-05, Vol.41 (5), p.389-393 |
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| container_end_page | 393 |
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| container_issue | 5 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
| container_volume | 41 |
| creator | Conradi, S Ronnevi, L O Vesterberg, O |
| description | The levels of lead in plasma were determined in 16 cases of amyotrophic lateral sclerosis (ALS) and 18 control subjects, using flameless atomic absorption spectrophotometry. The mean values were 0.52+/-0.22 microgram/100ml (ALS) and 0.37+/-0.13 microgram/100ml (controls), the difference is statistically significant (5% level). The values in both groups are lower than reported earlier for normal subjects. The findings are discussed against the background of the possible pathogenetic significance of retrograde axoplasmic flow in ALS. |
| doi_str_mv | 10.1136/jnnp.41.5.389 |
| format | Article |
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The mean values were 0.52+/-0.22 microgram/100ml (ALS) and 0.37+/-0.13 microgram/100ml (controls), the difference is statistically significant (5% level). The values in both groups are lower than reported earlier for normal subjects. The findings are discussed against the background of the possible pathogenetic significance of retrograde axoplasmic flow in ALS.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.41.5.389</identifier><identifier>PMID: 77896</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Amyotrophic Lateral Sclerosis - blood ; Amyotrophic Lateral Sclerosis - metabolism ; Axonal Transport ; Female ; Humans ; Lead - blood ; Lead - metabolism ; Male ; Middle Aged ; Neuromuscular Junction - metabolism ; Spectrophotometry, Atomic</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 1978-05, Vol.41 (5), p.389-393</ispartof><rights>Copyright BMJ Publishing Group LTD May 1978</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b447t-68bc4ae9539dadfe86aed6f36e8ff28b82dace9ea6ddb992f17f16ac6d3450d13</citedby><cites>FETCH-LOGICAL-b447t-68bc4ae9539dadfe86aed6f36e8ff28b82dace9ea6ddb992f17f16ac6d3450d13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC493043/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC493043/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/77896$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Conradi, S</creatorcontrib><creatorcontrib>Ronnevi, L O</creatorcontrib><creatorcontrib>Vesterberg, O</creatorcontrib><title>Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>The levels of lead in plasma were determined in 16 cases of amyotrophic lateral sclerosis (ALS) and 18 control subjects, using flameless atomic absorption spectrophotometry. The mean values were 0.52+/-0.22 microgram/100ml (ALS) and 0.37+/-0.13 microgram/100ml (controls), the difference is statistically significant (5% level). The values in both groups are lower than reported earlier for normal subjects. The findings are discussed against the background of the possible pathogenetic significance of retrograde axoplasmic flow in ALS.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Amyotrophic Lateral Sclerosis - blood</subject><subject>Amyotrophic Lateral Sclerosis - metabolism</subject><subject>Axonal Transport</subject><subject>Female</subject><subject>Humans</subject><subject>Lead - blood</subject><subject>Lead - metabolism</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neuromuscular Junction - metabolism</subject><subject>Spectrophotometry, Atomic</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkUGP0zAQhSPECsrCkRMXS1y4pNixYycHDqhQWGkFSMCKmzWxJ9QliYPtLvQ_8SNxt6sCJ3yxpfe9NzOeonjM6JIxLp9vp2leCrasl7xp7xQLJmRTck6_3C0WlFZVyWlN7xcPYtzSw2nae8WZUk0rF8Wvi8kEhIiWzAPEEciA1zhE4vv8AkvcRGZIDqcUyQ-XNgTGvU_BzxtnyAAJAwwkmgGDjy4S48cZQk67YY2fMpr1XbdFkxMgEovZM7opM92e9AOMOGDMUvJjjoQu-jAn5ycS5-w5VPJZwhT2D4uzHoaIj27v8-Lz-vWn1dvy8v2bi9XLy7ITQqVSNp0RgG3NWwu2x0YCWtlziU3fV03XVBYMtgjS2q5tq56pnkkw0nJRU8v4efHimDvvuhGtycPnKfUc3Ahhrz04_a8yuY3-6q-1aDkVPPuf3vqD_77DmPTW78KUW9ZMqaqpWlqpTJVHyuSviwH7UwFG9WGx-rBYLZiudV5s5p_83dWJvtnknzQXE_48iRC-aam4qvW7q5X-oD6-EvJqrdeZf3bku3H7n8K_ARY6xAs</recordid><startdate>19780501</startdate><enddate>19780501</enddate><creator>Conradi, S</creator><creator>Ronnevi, L O</creator><creator>Vesterberg, O</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>5PM</scope></search><sort><creationdate>19780501</creationdate><title>Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry</title><author>Conradi, S ; Ronnevi, L O ; Vesterberg, O</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b447t-68bc4ae9539dadfe86aed6f36e8ff28b82dace9ea6ddb992f17f16ac6d3450d13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1978</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Amyotrophic Lateral Sclerosis - blood</topic><topic>Amyotrophic Lateral Sclerosis - metabolism</topic><topic>Axonal Transport</topic><topic>Female</topic><topic>Humans</topic><topic>Lead - blood</topic><topic>Lead - metabolism</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neuromuscular Junction - metabolism</topic><topic>Spectrophotometry, Atomic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Conradi, S</creatorcontrib><creatorcontrib>Ronnevi, L O</creatorcontrib><creatorcontrib>Vesterberg, O</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Conradi, S</au><au>Ronnevi, L O</au><au>Vesterberg, O</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>1978-05-01</date><risdate>1978</risdate><volume>41</volume><issue>5</issue><spage>389</spage><epage>393</epage><pages>389-393</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>The levels of lead in plasma were determined in 16 cases of amyotrophic lateral sclerosis (ALS) and 18 control subjects, using flameless atomic absorption spectrophotometry. The mean values were 0.52+/-0.22 microgram/100ml (ALS) and 0.37+/-0.13 microgram/100ml (controls), the difference is statistically significant (5% level). The values in both groups are lower than reported earlier for normal subjects. The findings are discussed against the background of the possible pathogenetic significance of retrograde axoplasmic flow in ALS.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>77896</pmid><doi>10.1136/jnnp.41.5.389</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0022-3050 |
| ispartof | Journal of neurology, neurosurgery and psychiatry, 1978-05, Vol.41 (5), p.389-393 |
| issn | 0022-3050 1468-330X |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Amyotrophic Lateral Sclerosis - blood Amyotrophic Lateral Sclerosis - metabolism Axonal Transport Female Humans Lead - blood Lead - metabolism Male Middle Aged Neuromuscular Junction - metabolism Spectrophotometry, Atomic |
| title | Increased plasma levels of lead in patients with amyotrophic lateral sclerosis compared with control subjects as determined by flameless atomic absorption spectrophotometry |
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