Extracellular matrix fibronectin initiates endothelium‐dependent arteriolar dilatation via the heparin‐binding, matricryptic RWRPK sequence of the first type III repeat of fibrillar fibronectin

Key points The local arteriolar dilatation produced by contraction of skeletal muscle is dependent upon multiple signalling mechanisms. In addition to the many metabolic signals that mediate this vasodilatation, we show here that the extracellular matrix protein fibronectin also contributes to the r...

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Veröffentlicht in:The Journal of physiology 2016-02, Vol.594 (3), p.687-697
Hauptverfasser: Sarelius, Ingrid H., Titus, Patricia A., Maimon, Nir, Okech, William, Wilke‐Mounts, Susan J., Brennan, James R., Hocking, Denise C.
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Sprache:eng
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