Individual differences in the neural signature of subjective value among older adults

Some healthy older adults show departures from standard decision-making patterns exhibited by younger adults. We asked if such departures are uniform or if heterogeneous aging processes can designate which older adults show differing decision patterns. Thirty-three healthy older adults with varying...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Social cognitive and affective neuroscience 2016-07, Vol.11 (7), p.1111-1120
Hauptverfasser: Halfmann, Kameko, Hedgcock, William, Kable, Joseph, Denburg, Natalie L
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1120
container_issue 7
container_start_page 1111
container_title Social cognitive and affective neuroscience
container_volume 11
creator Halfmann, Kameko
Hedgcock, William
Kable, Joseph
Denburg, Natalie L
description Some healthy older adults show departures from standard decision-making patterns exhibited by younger adults. We asked if such departures are uniform or if heterogeneous aging processes can designate which older adults show differing decision patterns. Thirty-three healthy older adults with varying decision-making patterns on a complex decision task (the Iowa Gambling Task) completed an intertemporal choice task while undergoing functional magnetic resonance imaging. We examined whether value representation in the canonical valuation network differed across older adults based on complex decision-making ability. Older adults with advantageous decision patterns showed increased activity in the valuation network, including the ventromedial prefrontal cortex (VMPFC) and striatum. In contrast, older adults with disadvantageous decision patterns showed reduced or absent activation in the VMPFC and striatum, and these older adults also showed greater blood oxygen level dependent signal temporal variability in the striatum. Our results suggest that a reduced representation of value in the brain, possibly driven by increased neural noise, relates to suboptimal decision-making in a subset of older adults, which could translate to poor decision-making in many aspects of life, including finance, health and long-term care. Understanding the connection between suboptimal decision-making and neural value signals is a step toward mitigating age-related decision-making impairments.
doi_str_mv 10.1093/scan/nsv078
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4927033</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1801432593</sourcerecordid><originalsourceid>FETCH-LOGICAL-c414t-e204524554213f14af49ba8300d0fcfe07188dd35d4631f0c87d26c4295881873</originalsourceid><addsrcrecordid>eNqNkU1LJDEQhoMo6qon70uOgoxWPro7uQgiuisIXvQcMklljPSk3aTTsP_eGUYHvXmqgnp4eYuHkFMGFwy0uCzOpstUJujUDjlkndSzBrjc3e6sPSC_SnkFaLQEsU8OeAtKC8kPyfN98nGKvtqe-hgCZkwOC42Jji9IE9a8upS4SHasGekQaKnzV3RjnJBOtq9I7XJICzr0HjO1vvZjOSZ7wfYFTz7mEXm-u326-Tt7ePxzf3P9MHOSyXGGHGTDZdNIzkRg0gap51YJAA_BBYSOKeW9aLxsBQvgVOd56yTXjVJMdeKIXG1y3-p8id5hGld1zVuOS5v_m8FG8_2S4otZDJORmncgxCrg7CMgD_8qltEsY3HY9zbhUIthClSrW83YT1AmBW_0OvV8g7o8lJIxbBsxMGtnZu3MbJyt6N9fn9iyn5LEO8L5lFo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1801432593</pqid></control><display><type>article</type><title>Individual differences in the neural signature of subjective value among older adults</title><source>MEDLINE</source><source>Free E-Journal (出版社公開部分のみ)</source><source>PubMed Central</source><source>Oxford Open Access Journals</source><creator>Halfmann, Kameko ; Hedgcock, William ; Kable, Joseph ; Denburg, Natalie L</creator><creatorcontrib>Halfmann, Kameko ; Hedgcock, William ; Kable, Joseph ; Denburg, Natalie L</creatorcontrib><description>Some healthy older adults show departures from standard decision-making patterns exhibited by younger adults. We asked if such departures are uniform or if heterogeneous aging processes can designate which older adults show differing decision patterns. Thirty-three healthy older adults with varying decision-making patterns on a complex decision task (the Iowa Gambling Task) completed an intertemporal choice task while undergoing functional magnetic resonance imaging. We examined whether value representation in the canonical valuation network differed across older adults based on complex decision-making ability. Older adults with advantageous decision patterns showed increased activity in the valuation network, including the ventromedial prefrontal cortex (VMPFC) and striatum. In contrast, older adults with disadvantageous decision patterns showed reduced or absent activation in the VMPFC and striatum, and these older adults also showed greater blood oxygen level dependent signal temporal variability in the striatum. Our results suggest that a reduced representation of value in the brain, possibly driven by increased neural noise, relates to suboptimal decision-making in a subset of older adults, which could translate to poor decision-making in many aspects of life, including finance, health and long-term care. Understanding the connection between suboptimal decision-making and neural value signals is a step toward mitigating age-related decision-making impairments.</description><identifier>ISSN: 1749-5016</identifier><identifier>EISSN: 1749-5024</identifier><identifier>DOI: 10.1093/scan/nsv078</identifier><identifier>PMID: 26089342</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Aged ; Aging - physiology ; Brain Mapping ; Choice Behavior - physiology ; Corpus Striatum - physiology ; Decision Making - physiology ; Female ; Gambling - psychology ; Humans ; Individuality ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neuropsychological Tests ; Original ; Oxygen - blood ; Prefrontal Cortex - physiology</subject><ispartof>Social cognitive and affective neuroscience, 2016-07, Vol.11 (7), p.1111-1120</ispartof><rights>The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.</rights><rights>The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-e204524554213f14af49ba8300d0fcfe07188dd35d4631f0c87d26c4295881873</citedby><cites>FETCH-LOGICAL-c414t-e204524554213f14af49ba8300d0fcfe07188dd35d4631f0c87d26c4295881873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927033/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927033/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26089342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Halfmann, Kameko</creatorcontrib><creatorcontrib>Hedgcock, William</creatorcontrib><creatorcontrib>Kable, Joseph</creatorcontrib><creatorcontrib>Denburg, Natalie L</creatorcontrib><title>Individual differences in the neural signature of subjective value among older adults</title><title>Social cognitive and affective neuroscience</title><addtitle>Soc Cogn Affect Neurosci</addtitle><description>Some healthy older adults show departures from standard decision-making patterns exhibited by younger adults. We asked if such departures are uniform or if heterogeneous aging processes can designate which older adults show differing decision patterns. Thirty-three healthy older adults with varying decision-making patterns on a complex decision task (the Iowa Gambling Task) completed an intertemporal choice task while undergoing functional magnetic resonance imaging. We examined whether value representation in the canonical valuation network differed across older adults based on complex decision-making ability. Older adults with advantageous decision patterns showed increased activity in the valuation network, including the ventromedial prefrontal cortex (VMPFC) and striatum. In contrast, older adults with disadvantageous decision patterns showed reduced or absent activation in the VMPFC and striatum, and these older adults also showed greater blood oxygen level dependent signal temporal variability in the striatum. Our results suggest that a reduced representation of value in the brain, possibly driven by increased neural noise, relates to suboptimal decision-making in a subset of older adults, which could translate to poor decision-making in many aspects of life, including finance, health and long-term care. Understanding the connection between suboptimal decision-making and neural value signals is a step toward mitigating age-related decision-making impairments.</description><subject>Aged</subject><subject>Aging - physiology</subject><subject>Brain Mapping</subject><subject>Choice Behavior - physiology</subject><subject>Corpus Striatum - physiology</subject><subject>Decision Making - physiology</subject><subject>Female</subject><subject>Gambling - psychology</subject><subject>Humans</subject><subject>Individuality</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neuropsychological Tests</subject><subject>Original</subject><subject>Oxygen - blood</subject><subject>Prefrontal Cortex - physiology</subject><issn>1749-5016</issn><issn>1749-5024</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1LJDEQhoMo6qon70uOgoxWPro7uQgiuisIXvQcMklljPSk3aTTsP_eGUYHvXmqgnp4eYuHkFMGFwy0uCzOpstUJujUDjlkndSzBrjc3e6sPSC_SnkFaLQEsU8OeAtKC8kPyfN98nGKvtqe-hgCZkwOC42Jji9IE9a8upS4SHasGekQaKnzV3RjnJBOtq9I7XJICzr0HjO1vvZjOSZ7wfYFTz7mEXm-u326-Tt7ePxzf3P9MHOSyXGGHGTDZdNIzkRg0gap51YJAA_BBYSOKeW9aLxsBQvgVOd56yTXjVJMdeKIXG1y3-p8id5hGld1zVuOS5v_m8FG8_2S4otZDJORmncgxCrg7CMgD_8qltEsY3HY9zbhUIthClSrW83YT1AmBW_0OvV8g7o8lJIxbBsxMGtnZu3MbJyt6N9fn9iyn5LEO8L5lFo</recordid><startdate>20160701</startdate><enddate>20160701</enddate><creator>Halfmann, Kameko</creator><creator>Hedgcock, William</creator><creator>Kable, Joseph</creator><creator>Denburg, Natalie L</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope><scope>5PM</scope></search><sort><creationdate>20160701</creationdate><title>Individual differences in the neural signature of subjective value among older adults</title><author>Halfmann, Kameko ; Hedgcock, William ; Kable, Joseph ; Denburg, Natalie L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-e204524554213f14af49ba8300d0fcfe07188dd35d4631f0c87d26c4295881873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aged</topic><topic>Aging - physiology</topic><topic>Brain Mapping</topic><topic>Choice Behavior - physiology</topic><topic>Corpus Striatum - physiology</topic><topic>Decision Making - physiology</topic><topic>Female</topic><topic>Gambling - psychology</topic><topic>Humans</topic><topic>Individuality</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neuropsychological Tests</topic><topic>Original</topic><topic>Oxygen - blood</topic><topic>Prefrontal Cortex - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Halfmann, Kameko</creatorcontrib><creatorcontrib>Hedgcock, William</creatorcontrib><creatorcontrib>Kable, Joseph</creatorcontrib><creatorcontrib>Denburg, Natalie L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Social cognitive and affective neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Halfmann, Kameko</au><au>Hedgcock, William</au><au>Kable, Joseph</au><au>Denburg, Natalie L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Individual differences in the neural signature of subjective value among older adults</atitle><jtitle>Social cognitive and affective neuroscience</jtitle><addtitle>Soc Cogn Affect Neurosci</addtitle><date>2016-07-01</date><risdate>2016</risdate><volume>11</volume><issue>7</issue><spage>1111</spage><epage>1120</epage><pages>1111-1120</pages><issn>1749-5016</issn><eissn>1749-5024</eissn><abstract>Some healthy older adults show departures from standard decision-making patterns exhibited by younger adults. We asked if such departures are uniform or if heterogeneous aging processes can designate which older adults show differing decision patterns. Thirty-three healthy older adults with varying decision-making patterns on a complex decision task (the Iowa Gambling Task) completed an intertemporal choice task while undergoing functional magnetic resonance imaging. We examined whether value representation in the canonical valuation network differed across older adults based on complex decision-making ability. Older adults with advantageous decision patterns showed increased activity in the valuation network, including the ventromedial prefrontal cortex (VMPFC) and striatum. In contrast, older adults with disadvantageous decision patterns showed reduced or absent activation in the VMPFC and striatum, and these older adults also showed greater blood oxygen level dependent signal temporal variability in the striatum. Our results suggest that a reduced representation of value in the brain, possibly driven by increased neural noise, relates to suboptimal decision-making in a subset of older adults, which could translate to poor decision-making in many aspects of life, including finance, health and long-term care. Understanding the connection between suboptimal decision-making and neural value signals is a step toward mitigating age-related decision-making impairments.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>26089342</pmid><doi>10.1093/scan/nsv078</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1749-5016
ispartof Social cognitive and affective neuroscience, 2016-07, Vol.11 (7), p.1111-1120
issn 1749-5016
1749-5024
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4927033
source MEDLINE; Free E-Journal (出版社公開部分のみ); PubMed Central; Oxford Open Access Journals
subjects Aged
Aging - physiology
Brain Mapping
Choice Behavior - physiology
Corpus Striatum - physiology
Decision Making - physiology
Female
Gambling - psychology
Humans
Individuality
Magnetic Resonance Imaging
Male
Middle Aged
Neuropsychological Tests
Original
Oxygen - blood
Prefrontal Cortex - physiology
title Individual differences in the neural signature of subjective value among older adults
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T05%3A53%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Individual%20differences%20in%20the%20neural%20signature%20of%20subjective%20value%20among%20older%20adults&rft.jtitle=Social%20cognitive%20and%20affective%20neuroscience&rft.au=Halfmann,%20Kameko&rft.date=2016-07-01&rft.volume=11&rft.issue=7&rft.spage=1111&rft.epage=1120&rft.pages=1111-1120&rft.issn=1749-5016&rft.eissn=1749-5024&rft_id=info:doi/10.1093/scan/nsv078&rft_dat=%3Cproquest_pubme%3E1801432593%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1801432593&rft_id=info:pmid/26089342&rfr_iscdi=true