An implant to empty the bladder or close the urethra
An implant has been designed which, in the baboon, will empty the bladder almost completely, or close the urethra so that urine does not leak out despite a contraction of the detrusor muscle. Electrodes on the 1st and 2nd sacral anterior nerve roots (corresponding roughly to the 3rd and 4th sacral i...
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| Veröffentlicht in: | Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1977-04, Vol.40 (4), p.358-369 |
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| container_title | Journal of neurology, neurosurgery and psychiatry |
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| creator | Brindley, G S |
| description | An implant has been designed which, in the baboon, will empty the bladder almost completely, or close the urethra so that urine does not leak out despite a contraction of the detrusor muscle. Electrodes on the 1st and 2nd sacral anterior nerve roots (corresponding roughly to the 3rd and 4th sacral in man) suffice for both actions. Closing the urethra or emptying the bladder artificially in this way seems to cause conscious, neurologically intact, baboons no discomfort. Implants have remained in place for over two years, and have emptied the bladder artificially 12 times a day for many weeks, without deterioration of function. |
| doi_str_mv | 10.1136/jnnp.40.4.358 |
| format | Article |
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Implants have remained in place for over two years, and have emptied the bladder artificially 12 times a day for many weeks, without deterioration of function.</description><identifier>ISSN: 0022-3050</identifier><identifier>EISSN: 1468-330X</identifier><identifier>DOI: 10.1136/jnnp.40.4.358</identifier><identifier>PMID: 406364</identifier><identifier>CODEN: JNNPAU</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Animals ; Electric Stimulation - methods ; Electrodes, Implanted ; Evoked Potentials ; Haplorhini ; Male ; Muscle, Smooth - physiology ; Papio ; Postoperative Complications ; Spinal Nerve Roots - physiology ; Urethra - innervation ; Urinary Bladder - innervation ; Urinary Incontinence - therapy ; Urination</subject><ispartof>Journal of neurology, neurosurgery and psychiatry, 1977-04, Vol.40 (4), p.358-369</ispartof><rights>Copyright BMJ Publishing Group LTD Apr 1977</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b479t-dff7d2f192d396db6f8c098757554dc7c25b6457622e63a2891906d2adc636603</citedby><cites>FETCH-LOGICAL-b479t-dff7d2f192d396db6f8c098757554dc7c25b6457622e63a2891906d2adc636603</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC492703/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC492703/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/406364$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brindley, G S</creatorcontrib><title>An implant to empty the bladder or close the urethra</title><title>Journal of neurology, neurosurgery and psychiatry</title><addtitle>J Neurol Neurosurg Psychiatry</addtitle><description>An implant has been designed which, in the baboon, will empty the bladder almost completely, or close the urethra so that urine does not leak out despite a contraction of the detrusor muscle. 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Implants have remained in place for over two years, and have emptied the bladder artificially 12 times a day for many weeks, without deterioration of function.</description><subject>Animals</subject><subject>Electric Stimulation - methods</subject><subject>Electrodes, Implanted</subject><subject>Evoked Potentials</subject><subject>Haplorhini</subject><subject>Male</subject><subject>Muscle, Smooth - physiology</subject><subject>Papio</subject><subject>Postoperative Complications</subject><subject>Spinal Nerve Roots - physiology</subject><subject>Urethra - innervation</subject><subject>Urinary Bladder - innervation</subject><subject>Urinary Incontinence - therapy</subject><subject>Urination</subject><issn>0022-3050</issn><issn>1468-330X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkUmP1DAQhS3E1gwcuXGIhIS4pKnYjpfDHEYtVg0gxDa3khM7dJokDraDmH-Pmx41y4W6WKr6qvyqHiH3K1hXFRNPdtM0rzms-ZrV6hpZVVyokjG4uE5WAJSWDGq4Te7EuIN9KH2L3OQgmOArws-moh_nwUypSL5w45wui7R1RTMYa10ofCjawUf3K7kEl7bB3CU3OjNEd-_qPSEfnz39sHlRnr99_nJzdl42XOpU2q6TlnaVppZpYRvRqRa0krWsa25b2dK6EbyWglInmKFKVxqEpca2WZwAdkJOD3PnpRmdbd2UghlwDv1owiV60-Pflanf4hf_HbmmEljuf3TVH_y3xcWEYx9bN-RtnV8iKqYVKKAZfPgPuPNLmPJuWElJM5RvmKnyQLXBxxhcd1RSAe6twL0VyAE5Zisy_-BP-Uf6cPvf4_qY3I9j1YSvKCSTNb75tMF39PPF-1evGe5FPj7wzbj7z88_AVl7n_k</recordid><startdate>19770401</startdate><enddate>19770401</enddate><creator>Brindley, G S</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19770401</creationdate><title>An implant to empty the bladder or close the urethra</title><author>Brindley, G S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b479t-dff7d2f192d396db6f8c098757554dc7c25b6457622e63a2891906d2adc636603</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Animals</topic><topic>Electric Stimulation - methods</topic><topic>Electrodes, Implanted</topic><topic>Evoked Potentials</topic><topic>Haplorhini</topic><topic>Male</topic><topic>Muscle, Smooth - physiology</topic><topic>Papio</topic><topic>Postoperative Complications</topic><topic>Spinal Nerve Roots - physiology</topic><topic>Urethra - innervation</topic><topic>Urinary Bladder - innervation</topic><topic>Urinary Incontinence - therapy</topic><topic>Urination</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brindley, G S</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brindley, G S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An implant to empty the bladder or close the urethra</atitle><jtitle>Journal of neurology, neurosurgery and psychiatry</jtitle><addtitle>J Neurol Neurosurg Psychiatry</addtitle><date>1977-04-01</date><risdate>1977</risdate><volume>40</volume><issue>4</issue><spage>358</spage><epage>369</epage><pages>358-369</pages><issn>0022-3050</issn><eissn>1468-330X</eissn><coden>JNNPAU</coden><abstract>An implant has been designed which, in the baboon, will empty the bladder almost completely, or close the urethra so that urine does not leak out despite a contraction of the detrusor muscle. Electrodes on the 1st and 2nd sacral anterior nerve roots (corresponding roughly to the 3rd and 4th sacral in man) suffice for both actions. Closing the urethra or emptying the bladder artificially in this way seems to cause conscious, neurologically intact, baboons no discomfort. Implants have remained in place for over two years, and have emptied the bladder artificially 12 times a day for many weeks, without deterioration of function.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>406364</pmid><doi>10.1136/jnnp.40.4.358</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0022-3050 |
| ispartof | Journal of neurology, neurosurgery and psychiatry, 1977-04, Vol.40 (4), p.358-369 |
| issn | 0022-3050 1468-330X |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_492703 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Animals Electric Stimulation - methods Electrodes, Implanted Evoked Potentials Haplorhini Male Muscle, Smooth - physiology Papio Postoperative Complications Spinal Nerve Roots - physiology Urethra - innervation Urinary Bladder - innervation Urinary Incontinence - therapy Urination |
| title | An implant to empty the bladder or close the urethra |
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