Phosphorylated-insulin growth factor I receptor (p-IGF1R) and metalloproteinase-3 (MMP3) expression in advanced gastrointestinal stromal tumors (GIST). A GEIS 19 study

Most GISTs have mutations in KIT or PDGFRA. Patients with advanced GIST with KIT exon 9, PDGFRA mutation or WT for KIT and PDGFRA have a worse progression-free survival (PFS) compared to patients with KIT exon 11 mutated tumors. We evaluated the immunohistochemical (IHC) expression of p-IGF1R (Y1316...

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Veröffentlicht in:Clinical sarcoma research 2016-06, Vol.6 (1), p.10-10, Article 10
Hauptverfasser: Maurel, Joan, López-Pousa, Antonio, Calabuig, Silvia, Bagué, Silvia, Del Muro, Xavier Garcia, Sanjuan, Xavier, Rubió-Casadevall, Jordi, Cuatrecasas, Miriam, Martinez-Trufero, Javier, Horndler, Carlos, Fra, Joaquin, Valverde, Claudia, Redondo, Andrés, Poveda, Andrés, Sevilla, Isabel, Lainez, Nuria, Rubini, Michele, García-Albéniz, Xabier, Martín-Broto, Javier, de Alava, Enrique
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Sprache:eng
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