Oxidative Stress Related Diseases in Newborns
We review oxidative stress-related newborn disease and the mechanism of oxidative damage. In addition, we outline diagnostic and therapeutic strategies and future directions. Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogen species and the lack...
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| Veröffentlicht in: | Oxidative medicine and cellular longevity 2016-01, Vol.2016 (2016), p.1-9 |
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| container_title | Oxidative medicine and cellular longevity |
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| creator | Ozsurekci, Yasemin Aykac, Kubra |
| description | We review oxidative stress-related newborn disease and the mechanism of oxidative damage. In addition, we outline diagnostic and therapeutic strategies and future directions. Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogen species and the lack of protective ability of antioxidants. From that point of view, free radical-induced damage caused by oxidative stress seems to be a probable contributing factor to the pathogenesis of many newborn diseases, such as respiratory distress syndrome, bronchopulmonary dysplasia, periventricular leukomalacia, necrotizing enterocolitis, patent ductus arteriosus, and retinopathy of prematurity. We share the hope that the new understanding of the concept of oxidative stress and its relation to newborn diseases that has been made possible by new diagnostic techniques will throw light on the treatment of those diseases. |
| doi_str_mv | 10.1155/2016/2768365 |
| format | Article |
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In addition, we outline diagnostic and therapeutic strategies and future directions. Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogen species and the lack of protective ability of antioxidants. From that point of view, free radical-induced damage caused by oxidative stress seems to be a probable contributing factor to the pathogenesis of many newborn diseases, such as respiratory distress syndrome, bronchopulmonary dysplasia, periventricular leukomalacia, necrotizing enterocolitis, patent ductus arteriosus, and retinopathy of prematurity. 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This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><rights>Copyright © 2016 Y. Ozsurekci and K. 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In addition, we outline diagnostic and therapeutic strategies and future directions. Many reports have defined oxidative stress as an imbalance between an enhanced reactive oxygen/nitrogen species and the lack of protective ability of antioxidants. From that point of view, free radical-induced damage caused by oxidative stress seems to be a probable contributing factor to the pathogenesis of many newborn diseases, such as respiratory distress syndrome, bronchopulmonary dysplasia, periventricular leukomalacia, necrotizing enterocolitis, patent ductus arteriosus, and retinopathy of prematurity. We share the hope that the new understanding of the concept of oxidative stress and its relation to newborn diseases that has been made possible by new diagnostic techniques will throw light on the treatment of those diseases.</description><subject>Antioxidants</subject><subject>Congenital heart disease</subject><subject>DNA methylation</subject><subject>Dysplasia</subject><subject>Female</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Infant, Premature, Diseases - etiology</subject><subject>Infants (Newborn)</subject><subject>Lipids</subject><subject>Male</subject><subject>Oxidation</subject><subject>Oxidative stress</subject><subject>Oxidative Stress - physiology</subject><subject>Respiratory Distress Syndrome, Newborn - etiology</subject><subject>Review</subject><subject>Studies</subject><issn>1942-0900</issn><issn>1942-0994</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkUtLJDEURoPM4HvnWgpmM-DUmJtXJZsB0XmBjOBjHdLJLY1UV2lS7ePfm6Z7Wp3VrBLI4eS79yNkD-hXACkPGQV1yBqluZJrZBOMYDU1RnxY3SndIFs531KqOBOwTjZYIyhnzGyS-uwpBjfGB6wuxoQ5V-fYuRFDdRIzuoy5in31Bx8nQ-rzDvnYui7j7vLcJlc_vl8e_6pPz37-Pj46rb1UcqwxcKkY1YZ7pwMY8EI6HxxwDS0VzEMz0cxLrzQTPph5dsNFCNh6rdSEb5NvC-_dbDLF4LEfk-vsXYpTl57t4KJ9_9LHG3s9PFhhmCr7KILPS0Ea7meYRzuN2WPXuR6HWbagKW8MNFwX9NM_6O0wS30Zz0JjjCzxmzfUtevQxr4dyr9-LrVHEiQwySUv1JcF5dOQc8J2FRmonbdl523ZZVsF33875gr-W08BDhbATeyDe4z_qcPCYOteaQDeCM5fALdxo54</recordid><startdate>20160101</startdate><enddate>20160101</enddate><creator>Ozsurekci, Yasemin</creator><creator>Aykac, Kubra</creator><general>Hindawi Publishing Corporation</general><general>John Wiley & Sons, Inc</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8662-6909</orcidid></search><sort><creationdate>20160101</creationdate><title>Oxidative Stress Related Diseases in Newborns</title><author>Ozsurekci, Yasemin ; 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| ispartof | Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-9 |
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| subjects | Antioxidants Congenital heart disease DNA methylation Dysplasia Female Humans Infant, Newborn Infant, Premature, Diseases - etiology Infants (Newborn) Lipids Male Oxidation Oxidative stress Oxidative Stress - physiology Respiratory Distress Syndrome, Newborn - etiology Review Studies |
| title | Oxidative Stress Related Diseases in Newborns |
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