Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex

During evolution, the neocortex has expanded dramatically and folded in certain species, providing superior sensorimotor and cognitive abilities. Expansion of neural progenitors called bRGs and IPCs plays key roles in expansion and folding of the neocortex. Using mouse models, comparative genomics a...

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Veröffentlicht in:Nature neuroscience 2016-07, Vol.19 (7), p.888-896
Hauptverfasser: Wang, Lei, Hou, Shirui, Han, Young-Goo
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Sprache:eng
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