Concentration Ranges of Antibacterial Cations for Showing the Highest Antibacterial Efficacy but the Least Cytotoxicity against Mammalian Cells: Implications for a New Antibacterial Mechanism

Antibacterial metal ions, such as Ag+, Zn2+ and Cu2+, have been extensively used in medical implants and devices due to their strong broad spectrum of antibacterial activity. However, it is still a controversial issue as to whether they can show the desired antibacterial activity while being toxic t...

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Veröffentlicht in:	Chemical research in toxicology 2015-09, Vol.28 (9), p.1815-1822
Hauptverfasser:	Ning, Chengyun, Wang, Xiaolan, Li, Lihua, Zhu, Ye, Li, Mei, Yu, Peng, Zhou, Lei, Zhou, Zhengnan, Chen, Junqi, Tan, Guoxin, Zhang, Yu, Wang, Yingjun, Mao, Chuanbin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Cations Dose-Response Relationship, Drug Escherichia coli Escherichia coli - drug effects Metals - pharmacology Microbial Sensitivity Tests Microscopy, Electron, Transmission Staphylococcus aureus Staphylococcus aureus - drug effects
Online-Zugang:	Volltext
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